diff --git a/Source/Tools/ShaderConductorCmd.cpp b/Source/Tools/ShaderConductorCmd.cpp
index 239be581..c0c3cd11 100644
--- a/Source/Tools/ShaderConductorCmd.cpp
+++ b/Source/Tools/ShaderConductorCmd.cpp
@@ -48,7 +48,9 @@ int main(int argc, char** argv)
         ("I,input", "Input file name", cxxopts::value<std::string>())("O,output", "Output file name", cxxopts::value<std::string>())
         ("S,stage", "Shader stage: vs, ps, gs, hs, ds, cs", cxxopts::value<std::string>())
         ("T,target", "Target shading language: dxil, spirv, hlsl, glsl, essl, msl_macos, msl_ios", cxxopts::value<std::string>()->default_value("dxil"))
-        ("V,version", "The version of target shading language", cxxopts::value<std::string>()->default_value(""));
+        ("V,version", "The version of target shading language", cxxopts::value<std::string>()->default_value(""))
+        ("D,define", "Macro define as name=value", cxxopts::value<std::vector<std::string>>());
+
     // clang-format on
 
     auto opts = options.parse(argc, argv);
@@ -169,7 +171,43 @@ int main(int argc, char** argv)
     }
     sourceDesc.source = source.c_str();
 
-    // TODO: Support macro definition from command line
+    size_t numberOfDefines = opts.count("define");
+    std::vector<MacroDefine> macroDefines;
+    std::vector<std::string> macroStrings;
+    if (numberOfDefines > 0)
+    {
+        macroDefines.reserve(numberOfDefines);
+        macroStrings.reserve(numberOfDefines * 2);
+        auto& defines = opts["define"].as<std::vector<std::string>>();
+        for (const auto& define : defines)
+        {
+            MacroDefine macroDefine;
+            macroDefine.name = nullptr;
+            macroDefine.value = nullptr;
+
+            size_t splitPosition = define.find('=');
+            if (splitPosition != std::string::npos)
+            {
+                std::string macroName = define.substr(0, splitPosition);
+                std::string macroValue = define.substr(splitPosition + 1, define.size() - splitPosition - 1);
+
+                macroStrings.push_back(macroName);
+                macroDefine.name = macroStrings.back().c_str();
+                macroStrings.push_back(macroValue);
+                macroDefine.value = macroStrings.back().c_str();
+            }
+            else
+            {
+                macroStrings.push_back(define);
+                macroDefine.name = macroStrings.back().c_str();
+            }
+
+            macroDefines.push_back(macroDefine);
+        }
+
+        sourceDesc.defines = macroDefines.data();
+        sourceDesc.numDefines = static_cast<uint32_t>(macroDefines.size());
+    }
 
     try
     {
@@ -178,7 +216,7 @@ int main(int argc, char** argv)
         if (result.errorWarningMsg != nullptr)
         {
             const char* msg = reinterpret_cast<const char*>(result.errorWarningMsg->Data());
-            std::cerr << "Error or warning form shader compiler: " << std::endl
+            std::cerr << "Error or warning from shader compiler: " << std::endl
                       << std::string(msg, msg + result.errorWarningMsg->Size()) << std::endl;
         }
         if (result.target != nullptr)