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title abstract year volume publisher series software layout issn id month tex_title firstpage lastpage page order cycles bibtex_author author date address container-title genre issued pdf extras
Retrieving Evidence from EHRs with LLMs: Possibilities and Challenges
Unstructured data in Electronic Health Records (EHRs) often contains critical information—complementary to imaging—that could inform radiologists’ diagnoses. But the large volume of notes often associated with patients together with time constraints renders manually identifying relevant evidence practically infeasible. In this work we propose and evaluate a zero-shot strategy for using LLMs as a mechanism to efficiently retrieve and summarize unstructured evidence in patient EHR relevant to a given query. Our method entails tasking an LLM to infer whether a patient has, or is at risk of, a particular condition on the basis of associated notes; if so, we ask the model to summarize the supporting evidence. Under expert evaluation, we find that this LLM-based approach provides outputs consistently preferred to a pre-LLM information retrieval baseline. Manual evaluation is expensive, so we also propose and validate a method using an LLM to evaluate (other) LLM outputs for this task, allowing us to scale up evaluation. Our findings indicate the promise of LLMs as interfaces to EHR, but also highlight the outstanding challenge posed by “hallucinations”. In this setting, however, we show that model confidence in outputs strongly correlates with faithful summaries, offering a practical means to limit confabulations.
2024
248
PMLR
Proceedings of Machine Learning Research
inproceedings
2640-3498
ahsan24a
0
Retrieving Evidence from EHRs with LLMs: Possibilities and Challenges
489
505
489-505
489
false
Ahsan, Hiba and McInerney, Denis Jered and Kim, Jisoo and Potter, Christopher A and Young, Geoffrey and Amir, Silvio and Wallace, Byron C
given family
Hiba
Ahsan
given family
Denis Jered
McInerney
given family
Jisoo
Kim
given family
Christopher A
Potter
given family
Geoffrey
Young
given family
Silvio
Amir
given family
Byron C
Wallace
2024-07-24
Proceedings of the fifth Conference on Health, Inference, and Learning
inproceedings
date-parts
2024
7
24