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title abstract year volume publisher series software layout issn id month tex_title firstpage lastpage page order cycles bibtex_author author date address container-title genre issued pdf extras
Algorithmic Changes Are Not Enough: Evaluating the Removal of Race Adjustment From the eGFR Equation
Changing clinical algorithms to remove race adjustment has been proposed and implemented for multiple health conditions. Removing race adjustment from estimated glomerular filtration rate (eGFR) equations may reduce disparities in chronic kidney disease (CKD), but has not been studied in clinical practice after implementation. Here, we assessed whether implementing an eGFR equation (CKD-EPI 2021) without adjustment for Black or African American race modified quarterly rates of nephrology referrals and visits within a single healthcare system, Stanford Health Care (SHC). Our cohort study analyzed 547,194 adult patients aged 21 and older who had at least one recorded serum creatinine or serum cystatin C between January 1, 2019 and September 1, 2023. During the study period, implementation of CKD-EPI 2021 did not modify rates of quarterly nephrology referrals in those documented as Black or African American or in the overall cohort. After adjusting for capacity at SHC nephrology clinics, estimated rates of nephrology referrals and visits with CKD-EPI 2021 were 34 (95% CI 29, 39) and 188 (175, 201) per 10,000 patients documented as Black or African American. If race adjustment had not been removed, estimated rates were nearly identical: 38 (95% CI: 28, 53) and 189 (165, 218) per 10,000 patients. Changes to the eGFR equation are likely insufficient to achieve health equity in CKD care decision-making as many other structural inequities remain.
2024
248
PMLR
Proceedings of Machine Learning Research
inproceedings
2640-3498
cusick24a
0
Algorithmic Changes Are Not Enough: Evaluating the Removal of Race Adjustment From the eGFR Equation
619
643
619-643
619
false
Cusick, Marika M and Chertow, Glenn M and Owens, Douglas K and Williams, Michelle Y and Rose, Sherri
given family
Marika M
Cusick
given family
Glenn M
Chertow
given family
Douglas K
Owens
given family
Michelle Y
Williams
given family
Sherri
Rose
2024-07-24
Proceedings of the fifth Conference on Health, Inference, and Learning
inproceedings
date-parts
2024
7
24