title | abstract | layout | series | publisher | issn | id | month | tex_title | firstpage | lastpage | page | order | cycles | bibtex_author | author | date | address | container-title | volume | genre | issued | extras | ||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lupus Nephritis Subtype Classification with only Slide Level Labels |
Lupus Nephritis classification has historically relied on labor-intensive and meticulous glomerular-level labeling of renal structures in whole slide images (WSIs). However, this approach presents a formidable challenge due to its tedious and resource-intensive nature, limiting its scalability and practicality in clinical settings. In response to this challenge, our work introduces a novel methodology that utilizes only slide-level labels, eliminating the need for granular glomerular-level labeling. A comprehensive multi-stained lupus nephritis digital histopathology WSI dataset was created from the Indian population, which is the largest of its kind. LupusNet, a deep learning MIL-based model, was developed for the sub- type classification of LN. The results underscore its effectiveness, achieving an AUC score of 91.0%, an F1-score of 77.3%, and an accuracy of 81.1% on our dataset in distinguishing membranous and diffused classes of LN. |
inproceedings |
Proceedings of Machine Learning Research |
PMLR |
2640-3498 |
sharma24a |
0 |
Lupus Nephritis Subtype Classification with only Slide Level Labels |
1401 |
1411 |
1401-1411 |
1401 |
false |
Sharma, Amit and Chauhan, Ekansh and Uppin, Megha S and Rajasekhar, Liza and Jawahar, C.V. and Vinod, P K |
|
2024-12-23 |
Proceedings of The 7nd International Conference on Medical Imaging with Deep Learning |
250 |
inproceedings |
|