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cmungall committed Jun 2, 2018
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13 changes: 12 additions & 1 deletion Changes.md
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## 2018-06-01 Release

* [autoimmune retinopathy](http://purl.obolibrary.org/obo/MONDO_0100014)
* [adult-onset segmental dystonia](http://purl.obolibrary.org/obo/MONDO_0100015)
* [early-onset generalized dystonia](http://purl.obolibrary.org/obo/MONDO_0100016)
* [ECHS1-related paroxysmal dyskinesia](http://purl.obolibrary.org/obo/MONDO_0100019)
* [von Willebrand disease (hereditary or acquired)](http://purl.obolibrary.org/obo/MONDO_0024574)
* [familial hypertrophic cardiomyopathy](http://purl.obolibrary.org/obo/MONDO_0024573)
* [immunodeficiency-related disorder](http://purl.obolibrary.org/obo/MONDO_0024572)
* [AIDS-related disorder](http://purl.obolibrary.org/obo/MONDO_0024571)

## 2018-05-29 Release

New classes:

* [vascular bone neoplasm](http://purl.obolibrary.org/obo/MONDO_0024499)
* [vascular bone neoplasm](http://purl.obolibrary.org/obo/MONDO_0024499)
* [glioma susceptibility 1](http://purl.obolibrary.org/obo/MONDO_0024498)
* [familial chronic mucocutaneous candidiasis](http://purl.obolibrary.org/obo/MONDO_0024486)
* [papillary urothelial hyperplasia](http://purl.obolibrary.org/obo/MONDO_0024485)
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118 changes: 118 additions & 0 deletions src/ontology/imports/go_import.obo
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Expand Up @@ -3350,6 +3350,15 @@ intersection_of: GO:0006810 ! transport
intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region
relationship: BFO:0000066 GO:0005576 ! occurs in extracellular region

[Term]
id: GO:0006859
name: extracellular carbohydrate transport
def: "The directed extracellular movement of carbohydrates." []
is_a: GO:0006858 ! extracellular transport
is_a: GO:0008643 ! carbohydrate transport
intersection_of: GO:0008643 ! carbohydrate transport
intersection_of: BFO:0000066 GO:0005576 ! occurs in extracellular region

[Term]
id: GO:0006860
name: extracellular amino acid transport
Expand Down Expand Up @@ -4169,6 +4178,23 @@ is_a: GO:0042816 ! vitamin B6 metabolic process
is_a: GO:0051186 ! cofactor metabolic process
is_a: GO:1901615 ! organic hydroxy compound metabolic process

[Term]
id: GO:0008643
name: carbohydrate transport
def: "The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y." []
synonym: "sugar transport" NARROW []
is_a: GO:0071702 ! organic substance transport

[Term]
id: GO:0008645
name: hexose transmembrane transport
def: "The process in which hexose is transported across a membrane. Hexoses are any aldoses with a chain of six carbon atoms in the molecule." []
synonym: "hexose membrane transport" RELATED []
synonym: "hexose transport" RELATED []
synonym: "high-affinity hexose transport" NARROW []
synonym: "low-affinity hexose transport" NARROW []
is_a: GO:0015749 ! monosaccharide transmembrane transport

[Term]
id: GO:0008652
name: cellular amino acid biosynthetic process
Expand Down Expand Up @@ -5507,6 +5533,38 @@ intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002212 GO:0007005 ! negatively regulates mitochondrion organization
relationship: RO:0002212 GO:0007005 ! negatively regulates mitochondrion organization

[Term]
id: GO:0010827
name: regulation of glucose transmembrane transport
def: "Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." []
synonym: "regulation of glucose transport" RELATED []
is_a: GO:0034762 ! regulation of transmembrane transport
intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002211 GO:1904659 ! regulates glucose transmembrane transport
relationship: RO:0002211 GO:1904659 ! regulates glucose transmembrane transport

[Term]
id: GO:0010828
name: positive regulation of glucose transmembrane transport
def: "Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." []
synonym: "positive regulation of glucose transport" RELATED []
is_a: GO:0010827 ! regulation of glucose transmembrane transport
is_a: GO:0034764 ! positive regulation of transmembrane transport
intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002213 GO:1904659 ! positively regulates glucose transmembrane transport
relationship: RO:0002213 GO:1904659 ! positively regulates glucose transmembrane transport

[Term]
id: GO:0010829
name: negative regulation of glucose transmembrane transport
def: "Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore." []
synonym: "negative regulation of glucose transport" RELATED []
is_a: GO:0010827 ! regulation of glucose transmembrane transport
is_a: GO:0034763 ! negative regulation of transmembrane transport
intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002212 GO:1904659 ! negatively regulates glucose transmembrane transport
relationship: RO:0002212 GO:1904659 ! negatively regulates glucose transmembrane transport

[Term]
id: GO:0010876
name: lipid localization
Expand Down Expand Up @@ -5851,6 +5909,13 @@ def: "The directed movement of bilirubin into, out of or within a cell, or betwe
is_a: GO:0006835 ! dicarboxylic acid transport
is_a: GO:0071705 ! nitrogen compound transport

[Term]
id: GO:0015749
name: monosaccharide transmembrane transport
def: "The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides." []
synonym: "monosaccharide transport" RELATED []
is_a: GO:0034219 ! carbohydrate transmembrane transport

[Term]
id: GO:0015758
is_obsolete: true
Expand Down Expand Up @@ -7307,6 +7372,12 @@ synonym: "cholecalciferol 25-hydroxylase activity" EXACT []
is_a: GO:0070643 ! vitamin D 25-hydroxylase activity
relationship: BFO:0000050 GO:0036378 ! part of calcitriol biosynthetic process from calciol

[Term]
id: GO:0030421
name: defecation
def: "The expulsion of feces from the rectum." []
is_a: GO:0007588 ! excretion

[Term]
id: GO:0030424
name: axon
Expand Down Expand Up @@ -9018,6 +9089,15 @@ intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002213 GO:0048771 ! positively regulates tissue remodeling
relationship: RO:0002213 GO:0048771 ! positively regulates tissue remodeling

[Term]
id: GO:0034219
name: carbohydrate transmembrane transport
def: "The process in which a carbohydrate is transported across a membrane." []
synonym: "carbohydrate membrane transport" EXACT []
synonym: "transmembrane carbohydrate transport" EXACT []
is_a: GO:0008643 ! carbohydrate transport
is_a: GO:0055085 ! transmembrane transport

[Term]
id: GO:0034220
name: ion transmembrane transport
Expand Down Expand Up @@ -20275,6 +20355,13 @@ intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002213 GO:0061615 ! positively regulates glycolytic process through fructose-6-phosphate
relationship: RO:0002213 GO:0061615 ! positively regulates glycolytic process through fructose-6-phosphate

[Term]
id: GO:1904659
name: glucose transmembrane transport
def: "The process in which glucose is transported across a membrane." []
synonym: "glucose transport" RELATED []
is_a: GO:0008645 ! hexose transmembrane transport

[Term]
id: GO:1904729
name: regulation of intestinal lipid absorption
Expand Down Expand Up @@ -21252,6 +21339,37 @@ intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002213 GO:0008652 ! positively regulates cellular amino acid biosynthetic process
relationship: RO:0002213 GO:0008652 ! positively regulates cellular amino acid biosynthetic process

[Term]
id: GO:2000292
name: regulation of defecation
def: "Any process that modulates the frequency, rate or extent of defecation." []
is_a: GO:0044062 ! regulation of excretion
intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002211 GO:0030421 ! regulates defecation
relationship: RO:0002211 GO:0030421 ! regulates defecation

[Term]
id: GO:2000293
name: negative regulation of defecation
def: "Any process that stops, prevents or reduces the frequency, rate or extent of defecation." []
is_a: GO:0051048 ! negative regulation of secretion
is_a: GO:0051241 ! negative regulation of multicellular organismal process
is_a: GO:2000292 ! regulation of defecation
intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002212 GO:0030421 ! negatively regulates defecation
relationship: RO:0002212 GO:0030421 ! negatively regulates defecation

[Term]
id: GO:2000294
name: positive regulation of defecation
def: "Any process that activates or increases the frequency, rate or extent of defecation." []
is_a: GO:0051047 ! positive regulation of secretion
is_a: GO:0051240 ! positive regulation of multicellular organismal process
is_a: GO:2000292 ! regulation of defecation
intersection_of: GO:0008150 ! biological_process
intersection_of: RO:0002213 GO:0030421 ! positively regulates defecation
relationship: RO:0002213 GO:0030421 ! positively regulates defecation

[Term]
id: GO:2000310
name: regulation of NMDA receptor activity
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