diff --git a/resources/curated/dlbcl_genes.tsv b/resources/curated/dlbcl_genes.tsv index cd03d499..e33726c7 100644 --- a/resources/curated/dlbcl_genes.tsv +++ b/resources/curated/dlbcl_genes.tsv @@ -1,6 +1,6 @@ Gene Tier aSHM QC Mean variant quality citekey LymphGen PMID MutationEffect Mutation-PMID ACTB 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 -ACTG1 1 TRUE NA fanComprehensiveCharacterizationDriver2020b FALSE 33953289 +ACTG1 1 TRUE NA fanComprehensiveCharacterizationDriver2020b FALSE 32565964 ARID1A 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 LOF 38458187 ATM 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 11756177 B2M 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 22137796 @@ -17,29 +17,29 @@ CARD11 1 FALSE NA lenzOncogenicCARD11Mutations2008 FALSE 18323416 GOF 18323416 CCND3 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 GOF 22885699 CD58 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 22137796 CD70 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 36471481 -CD79B 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 GOF 29669863 +CD79B 1 FALSE NA davisChronicActiveBcellreceptor2010 TRUE 21796119 GOF 29669863 CD83 1 TRUE NA morinMutationalStructuralAnalysis2013 TRUE 23699601 CDKN2A 1 FALSE NA morinMutationalStructuralAnalysis2013 TRUE 23699601 LOF 19260062 CIITA 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 26549456 CREBBP 1 FALSE NA pasqualucciInactivatingMutationsAcetyltransferase2011a TRUE 21390126 LOF 33431788 CXCR4 1 TRUE NA khodabakhshiRecurrentTargetsAberrant2012 FALSE 23131835 LOF 36089616 -DDX3X 1 FALSE NA reddyGeneticFunctionalDrivers2017 TRUE LOF 34437837 +DDX3X 1 FALSE NA reddyGeneticFunctionalDrivers2017 TRUE 28985567 LOF 34437837 DTX1 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 LOF 28183850 DUSP2 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 EBF1 1 TRUE NA bohleRoleEarlyBcell2013 FALSE 23174882 LOF 28692033 -EEF1A1 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 33953289 +EEF1A1 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 EP300 1 FALSE NA pasqualucciInactivatingMutationsAcetyltransferase2011a TRUE 21390126 LOF 10700188 ETS1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 ETV6 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 24997145 EZH2 1 FALSE NA NA morinSomaticMutationsAltering2010a TRUE 20081860 GOF 21078963 FAS 1 FALSE NA schollMutationsRegionFAS2007 FALSE 17487740 LOF 20935634 -FBXO11 1 FALSE NA arthurGenomewideDiscoverySomatic2018 FALSE 33953289 LOF 22113614 +FBXO11 1 FALSE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 LOF 22113614 FBXW7 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 LOF 32350066 FOXO1 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 GOF 23460611 GNA13 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 26616858 GNAI2 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601 GOF 23699601 GRB2 1 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -GRHPR 1 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 30275490 +GRHPR 1 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966 HIST1H1B 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 HIST1H1C 1 TRUE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 HIST1H1D 1 TRUE NA morinMutationalStructuralAnalysis2013 FALSE 23699601 @@ -49,7 +49,7 @@ HIST1H2AM 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 HIST1H2BC 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 HIST1H2BK 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 HIST1H3B 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 -HIST2H2BE 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29641966 +HIST2H2BE 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 HLA-A 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 34050029 HLA-B 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 34050029 HLA-C 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 LOF 34050029 @@ -61,7 +61,7 @@ IL4R 1 TRUE NA dunsCharacterizationDLBCLPMBL2021b FALSE 33684939 GOF 29467182 IRF4 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 IRF8 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 38996030 ITPKB 1 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966 LOF 29650799 -JUNB 1 FALSE PASS 3 lohrDiscoveryPrioritizationSomatic2012a TRUE 28985567 +JUNB 1 FALSE PASS 3 lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 KLF2 1 TRUE NA pasqualucciAnalysisCodingGenome2011 TRUE 21804550 KLHL14 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 LOF 32127472 KLHL6 1 TRUE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 29695787 @@ -71,13 +71,13 @@ KRAS 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 GOF 9219 LRRN3 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 LTB 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 MEF2B 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 NEO 23974956; 26245647 -MEF2C 1 TRUE NA hubschmannMutationalMechanismsShaping2021b FALSE 30275490 -MGA 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 LOF 23039309 +MEF2C 1 TRUE NA hubschmannMutationalMechanismsShaping2021b FALSE 33953289 +MGA 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 23039309 MIR142 1 TRUE NA kwanhianMicroRNA142Mutated202012b FALSE 23342264 LOF 29724719 MPEG1 1 FALSE NA morinMutationalStructuralAnalysis2013 TRUE 23699601 MS4A1 1 TRUE NA rushtonGeneticEvolutionaryPatterns2020 FALSE 32589730 LOF 32589730 MTOR 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 GOF 24631838 -MYC 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a FALSE NA GOF 38565249 +MYC 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a FALSE 11460166 GOF 38565249 MYD88 1 FALSE NA ngoOncogenicallyActiveMYD882011a TRUE 21179087 GOF 21179087 NFKBIA 1 FALSE NA thomasMutationalAnalysisIkappaBalpha2004 TRUE 15198731 LOF 10637284 NFKBIE 1 FALSE NA morinGeneticLandscapesRelapsed2016 FALSE 26647218 LOF 25987724 @@ -88,55 +88,55 @@ NOTCH2 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 GOF 194450 OSBPL10 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 P2RY8 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 LOF 25274307 PIM1 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a TRUE 11460166 GOF 27904766 -PIM2 1 TRUE NA reddyGeneticFunctionalDrivers2017 TRUE 30275490 +PIM2 1 TRUE NA reddyGeneticFunctionalDrivers2017 TRUE 28985567 POU2AF1 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 LOF 30802265 POU2F2 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 LOF 26993806 PRDM1 1 FALSE NA pasqualucciInactivationPRDM1BLIMP12006a TRUE NA LOF 16492805 -PTEN 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE LOF 23840064 +PTEN 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 23840064 PTPN6 1 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 26565811 RB1 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601 LOF 17332242 -RFX7 1 FALSE NA NA arthurGenomewideDiscoverySomatic2018 FALSE NA LOF 30926791 +RFX7 1 FALSE NA NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 LOF 30926791 RHOA 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 LOF 26616858 RRAGC 1 FALSE NA okosunRecurrentMTORC1activatingRRAGC2016a FALSE 26691987 GOF 26691987 S1PR2 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 25274307 SETD1B 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945 LOF 21796119 -SF3B1 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE NEO 23160465 +SF3B1 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 NEO 23160465 SGK1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 GOF 33988691 SIN3A 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 -SMARCA4 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 22343534 LOF 33144586 +SMARCA4 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 33144586 SOCS1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 15572583 SPEN 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945 -STAT3 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 22343534 GOF 31861597 +STAT3 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 GOF 31861597 STAT6 1 FALSE NA yildizActivatingSTAT6Mutations2015c TRUE 25428220 GOF 35851155 TAF1 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601 TBL1XR1 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 32619424 TET2 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945 LOF 23831920 TMEM30A 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 32094924 -TMSB4X 1 TRUE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 +TMSB4X 1 TRUE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 TNFAIP3 1 FALSE NA compagnoMutationsMultipleGenes2009a TRUE 19412164 LOF 19412164 TNFRSF14 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 21796119 TOX 1 FALSE NA reddyGeneticFunctionalDrivers2017 TRUE 28985567 -TP53 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 22343534 LOF 12826609 +TP53 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 12826609 UBE2A 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 WEE1 1 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966 XPO1 1 FALSE NA mareschalWholeExomeSequencing2016 FALSE 26608593 NEO 33007990 ZC3H12A 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 LOF 19747262 ZFP36L1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 -ZNF292 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 -ZNF608 1 FALSE NA NA morinMutationalStructuralAnalysis2013 FALSE 23292937 -ARAP2 2 FALSE NA morinMutationalStructuralAnalysis2013 +ZNF292 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 +ZNF608 1 FALSE NA NA morinMutationalStructuralAnalysis2013 FALSE 23699601 +ARAP2 2 FALSE NA morinMutationalStructuralAnalysis2013 23699601 ADAMTSL3 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 AKAP8 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 ANKLE2 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -HIST1H3A 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a +HIST1H3A 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a 22343534 BCL2L10 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 BRSK1 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 C12orf35 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 CAMTA1 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -PTPN21 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a -RBP3 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a -TBP 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a -VAX1 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a +PTPN21 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a 22343534 +RBP3 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a 22343534 +TBP 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a 22343534 +VAX1 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a 22343534 ABI3BP 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 ADAMTS1 2 FALSE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 AICDA 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 @@ -175,12 +175,11 @@ DNAH5 2 FALSE PASS 4 morinMutationalStructuralAnalysis2013 FALSE 23699601 DNM2 2 FALSE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 DNMT3B 2 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 28327945 DOCK1 2 FALSE PASS 3 chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 -DSEL 2 FALSE morinMutationalStructuralAnalysis2013 DSG4 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 DPYD 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -EIF2AK3 2 TRUE NA NA schmitzGeneticsPathogenesisDiffuse2018a FALSE NA +EIF2AK3 2 TRUE NA NA schmitzGeneticsPathogenesisDiffuse2018a FALSE 29641966 DSC3 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -DSEL 2 FALSE NA morinMutationalStructuralAnalysis2013 +DSEL 2 FALSE NA morinMutationalStructuralAnalysis2013 23699601 ERAP2 2 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 28327945 EZR 2 TRUE NA NA NA FALSE NA FAM102A 2 TRUE NA NA NA FALSE NA @@ -206,19 +205,19 @@ HIST1H2AL 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 HIST1H2BO 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 HLA-DMA 2 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 HNF1B 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -HNRNPD 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE +HNRNPD 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 HNRNPH1 2 FALSE NA pararajalingamCodingNoncodingDrivers2020 FALSE 32160292 -ID3 2 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 22885699 +ID3 2 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966 IFNGR1 2 FALSE PASS 4 morinMutationalStructuralAnalysis2013 FALSE 23699601 IGLL5 2 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 IKBKB 2 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 IKBKE 2 FALSE PASS 4 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 -IL16 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE +IL16 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 IL6 2 FALSE PASS 3 chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 -INO80 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 +INO80 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 IRF1 2 TRUE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 -JAK1 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 -JAK3 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 +JAK1 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 +JAK3 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 KCMF1 2 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 KLHL21 2 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a FALSE 29641966 KRTAP5-5 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 @@ -243,7 +242,7 @@ MYOM2 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 NAV1 2 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 NCOA3 2 TRUE NA NA NA FALSE NA NEAT1 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 -NF1 2 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 28985567 +NF1 2 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 NLRP5 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 ODZ2 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 OR6K3 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 @@ -269,12 +268,12 @@ RAPGEF1 2 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 RCC 2 TRUE NA NA NA FALSE NA RFTN1 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 RFXAP 2 FALSE NA NA NA FALSE NA -RHEX 2 TRUE NA NA arthurGenomewideDiscoverySomatic2018 FALSE NA -RHOH 2 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a FALSE NA +RHEX 2 TRUE NA NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 +RHOH 2 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a FALSE 11460166 RUBCNL 2 TRUE NA NA NA FALSE NA S1PR1 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 SAMD9L 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 -SEL1L3 2 TRUE NA NA schmitzGeneticsPathogenesisDiffuse2018a FALSE NA +SEL1L3 2 TRUE NA NA schmitzGeneticsPathogenesisDiffuse2018a FALSE 29641966 SEPTIN9 2 TRUE NA NA NA FALSE NA SERPINA9 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 SETD2 2 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 @@ -287,13 +286,13 @@ SMEK1 2 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 SRPX 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 SRRM2 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 ST6GAL1 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 -STAT5B 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 +STAT5B 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 HMGB1 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 SYN2 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 SYPL1 2 FALSE PASS 3 morinMutationalStructuralAnalysis2013 FALSE 23699601 TAP1 2 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a FALSE 29641966 TBC1D4 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 -TCL1A 2 TRUE NA reddyGeneticFunctionalDrivers2017 FALSE +TCL1A 2 TRUE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 TGFBR2 2 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 TIPARP 2 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 TLR2 2 FALSE PASS 4 chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 @@ -302,8 +301,8 @@ TNF 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 TRAF3 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 TRAF6 2 FALSE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 TRIP12 2 FALSE NA NA NA FALSE NA -UBE2J1 2 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a FALSE NA -UBR5 2 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 23292937 +UBE2J1 2 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a FALSE 29641966 +UBR5 2 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 28327945 UHRF1BP1 2 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 28327945 UNC5B 2 FALSE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 UNC5C 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 @@ -314,7 +313,7 @@ WNK1 2 FALSE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 XBP1 2 TRUE NA NA FALSE NA YY1 2 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 ZCCHC7 2 TRUE NA arthurGenomewideDiscoverySomatic2018 FALSE 30275490 -ZEB2 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 +ZEB2 2 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 ZFX 2 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 ZNF217 2 FALSE PASS 3 hubschmannMutationalMechanismsShaping2021b FALSE 33953289 ZNF423 2 FALSE PASS 3 chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 @@ -332,10 +331,10 @@ SERPINA1 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 SMARCA1 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 TLL2 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 TSC22D1 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -ZNF385B 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a +ZNF385B 2 FALSE NA lohrDiscoveryPrioritizationSomatic2012a 22343534 ZNF521 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 ZWILCH 2 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550 -CDH1 3 FALSE NA fanComprehensiveCharacterizationDriver2020b +CDH1 3 FALSE NA fanComprehensiveCharacterizationDriver2020b 32565964 ABCA3 3 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 ABCA4 3 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 ABCB1 3 FALSE NA fanComprehensiveCharacterizationDriver2020b FALSE 32565964