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add extra support
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rdmorin committed Nov 27, 2024
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Showing 1 changed file with 113 additions and 113 deletions.
226 changes: 113 additions & 113 deletions resources/curated/fl_genes.tsv
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Gene Tier aSHM QC Mean Variant Quality citekey PMID MutationEffect Mutation-PMID
ACTB 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
ARID1A 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 38458187
ATP6AP1 1 okosunRecurrentMTORC1activatingRRAGC2016 26691987
ATP6V1B2 1 okosunRecurrentMTORC1activatingRRAGC2016 26691987 LOF 28064239
B2M 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 22137796
BCL10 1 russler-germainMutationsAssociatedProgression2023 37493986 GOF 35658124
BCL2 1 TRUE morinFrequentMutationHistonemodifying2011 21796119
BCL6 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 LOF 12504096
BCL7A 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 LOF 32576963
BTK 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 33419778
CARD11 1 morinFrequentMutationHistonemodifying2011 21796119 GOF 18323416
CCND3 1 morinFrequentMutationHistonemodifying2011 21796119 GOF 22885699
CD83 1 TRUE russler-germainMutationsAssociatedProgression2023 37493986
CREBBP 1 pasqualucciInactivatingMutationsAcetyltransferase2011 21390126 LOF 21390126
CTSS 1 barariaCathepsinAlterationsInduce2020 32330423 GOF 32330455
EBF1 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 LOF 28692033
EEF1A1 1 hubschmannMutationalMechanismsShaping2021 33953289
EP300 1 pasqualucciInactivatingMutationsAcetyltransferase2011 21390126 LOF 21390126
EZH2 1 morinSomaticMutationsAltering2010 20081860 GOF 21078963
FAS 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 20935634
FOXO1 1 morinFrequentMutationHistonemodifying2011 21796119 GOF 23460611
GNA13 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 26616858
GNAI2 1 drevalGeneticSubdivisionsFollicular2023 37084389
HIST1H1B 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H1C 1 TRUE morinFrequentMutationHistonemodifying2011 21796119
HIST1H1D 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H1E 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2AC 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2AG 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2AM 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2BC 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2BG 1 TRUE krysiakRecurrentSomaticMutations2017 28064239
HVCN1 1 krysiakRecurrentSomaticMutations2017 28064239
IRF4 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
IRF8 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 LOF 38996030
KLHL6 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 LOF 29695787
KMT2D 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 26366712
MAP2K1 1 louissaintPediatrictypeNodalFollicular2016 27325104 GOF 28533310
MEF2B 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 NEO 23974956; 26245647
MYC 1 TRUE rossiAberrantSomaticHypermutation2006 17018394 GOF 38565249
PIM1 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 GOF 27904766
POU2AF1 1 krysiakRecurrentSomaticMutations2017 28064239
POU2F2 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 26993806
RRAGC 1 okosunRecurrentMTORC1activatingRRAGC2016 26691987 GOF 26691987
SGK1 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 GOF 33988691
SMARCA4 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 33144586
SOCS1 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 LOF 15572583
STAT6 1 yildizActivatingSTAT6Mutations2015 25428220 GOF 35851155
TBL1XR1 1 drevalGeneticSubdivisionsFollicular2023 37084389 LOF 32619424
TMSB4X 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
TNFAIP3 1 drevalGeneticSubdivisionsFollicular2023 37084389 LOF 19412164
TNFRSF14 1 cheungAcquiredTNFRSF14Mutations2010 21796119
TP53 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 12826609
VMA21 1 hubschmannMutationalMechanismsShaping2021 33953289 LOF 35287545
ABL2 2 russler-germainMutationsAssociatedProgression2023 37563306
ACTG1 2 TRUE hubschmannMutationalMechanismsShaping2021 33953289
ATP6V1A 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
BTG1 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
BTG2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
CD70 2 russler-germainMutationsAssociatedProgression2023 37493986
CD79B 2 drevalGeneticSubdivisionsFollicular2023 37084389
CDC42BPB 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
CILP 2 russler-germainMutationsAssociatedProgression2023 37493986
CPNE8 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
CXCR4 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
CYP2A6 2 russler-germainMutationsAssociatedProgression2023 37493986
NEB 2 maSubtypespecificCooccurringGenetic2022 33792219
DDX3X 2 drevalGeneticSubdivisionsFollicular2023 37084389
DHX15 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
TPTE 2 maSubtypespecificCooccurringGenetic2022 33792219
DUSP2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
EGR1 2 krysiakRecurrentSomaticMutations2017 28064239
FZR1 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
GBP7 2 russler-germainMutationsAssociatedProgression2023 37563306
RHOA 2 maSubtypespecificCooccurringGenetic2022 33792219
GRM6 2 russler-germainMutationsAssociatedProgression2023 37493986
HIST1H2BD 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2BM 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
TBC1D3F 2 maSubtypespecificCooccurringGenetic2022 33792219
HIST1H3G 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H3I 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
IGLL5 2 TRUE russler-germainMutationsAssociatedProgression2023 37493986
ITPKB 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
JUP 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
KIR3DL1 2 russler-germainMutationsAssociatedProgression2023 37563306
KLF2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
LAPTM5 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
LTB 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
MAGEC1 2 russler-germainMutationsAssociatedProgression2023 37563306
MAP7D1 2 russler-germainMutationsAssociatedProgression2023 37563306
MEF2C 2 TRUE laurentFollicularLymphomaComprises2024 NA
MGEA5 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
MKI67 2 russler-germainMutationsAssociatedProgression2023 37493986
MYCBP2 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
MYD88 2 drevalGeneticSubdivisionsFollicular2023 37084389
NFKBIA 2 russler-germainMutationsAssociatedProgression2023 37493986
OR8H2 2 russler-germainMutationsAssociatedProgression2023 37493986
P2RY8 2 drevalGeneticSubdivisionsFollicular2023 37084389
PDS5B 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
PPP4C 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
PRKDC 2 hubschmannMutationalMechanismsShaping2021 33953289
PTPRD 2 drevalGeneticSubdivisionsFollicular2023 37084389
PZP 2 russler-germainMutationsAssociatedProgression2023 37493986
RBM6 2 hubschmannMutationalMechanismsShaping2021 33953289
S1PR2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
SHROOM3 2 russler-germainMutationsAssociatedProgression2023 37493986
SRRM2 2 russler-germainMutationsAssociatedProgression2023 37493986
STAB2 2 russler-germainMutationsAssociatedProgression2023 37493986
TMEM30A 2 morinFrequentMutationHistonemodifying2011 21796119
TPP1 2 hubschmannMutationalMechanismsShaping2021 33953289
XIRP2 2 russler-germainMutationsAssociatedProgression2023 37493986
ZNF608 2 krysiakRecurrentSomaticMutations2017 28064239
Gene Tier aSHM QC Mean Variant Quality citekey PMID MutationEffect Mutation-PMID Additional_Support
ACTB 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 kalmbachNovelInsightsPathogenesis2023
ARID1A 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 38458187 crouchMolecularSubclustersFollicular2022
ATP6AP1 1 okosunRecurrentMTORC1activatingRRAGC2016 26691987 drevalGeneticSubdivisionsFollicular2023
ATP6V1B2 1 okosunRecurrentMTORC1activatingRRAGC2016 26691987 LOF 28064239 drevalGeneticSubdivisionsFollicular2023
B2M 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 22137796 crouchMolecularSubclustersFollicular2022
BCL10 1 russler-germainMutationsAssociatedProgression2023 37493986 GOF 35658124 crouchMolecularSubclustersFollicular2022
BCL2 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 schuetzBCL2MutationsDiffuse2012
BCL6 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 LOF 12504096 crouchMolecularSubclustersFollicular2022
BCL7A 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 LOF 32576963 crouchMolecularSubclustersFollicular2022
BTK 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 33419778 crouchMolecularSubclustersFollicular2022
CARD11 1 morinFrequentMutationHistonemodifying2011 21796119 GOF 18323416 crouchMolecularSubclustersFollicular2022
CCND3 1 morinFrequentMutationHistonemodifying2011 21796119 GOF 22885699 crouchMolecularSubclustersFollicular2022
CD83 1 TRUE russler-germainMutationsAssociatedProgression2023 37493986 crouchMolecularSubclustersFollicular2022
CREBBP 1 pasqualucciInactivatingMutationsAcetyltransferase2011 21390126 LOF 21390126 morinFrequentMutationHistonemodifying2011
CTSS 1 barariaCathepsinAlterationsInduce2020 32330423 GOF 32330455 drevalGeneticSubdivisionsFollicular2023
EBF1 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 LOF 28692033 crouchMolecularSubclustersFollicular2022
EEF1A1 1 hubschmannMutationalMechanismsShaping2021 33953289 kalmbachNovelInsightsPathogenesis2023
EP300 1 pasqualucciInactivatingMutationsAcetyltransferase2011 21390126 LOF 21390126 morinFrequentMutationHistonemodifying2011
EZH2 1 morinSomaticMutationsAltering2010 20081860 GOF 21078963 drevalGeneticSubdivisionsFollicular2023
FAS 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 20935634 crouchMolecularSubclustersFollicular2022
FOXO1 1 morinFrequentMutationHistonemodifying2011 21796119 GOF 23460611 crouchMolecularSubclustersFollicular2022
GNA13 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 26616858 crouchMolecularSubclustersFollicular2022
GNAI2 1 drevalGeneticSubdivisionsFollicular2023 37084389 kalmbachNovelInsightsPathogenesis2023
HIST1H1B 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H1C 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 crouchMolecularSubclustersFollicular2022
HIST1H1D 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H1E 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H2AC 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H2AG 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H2AM 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H2BC 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HIST1H2BG 1 TRUE krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
HVCN1 1 krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
IRF8 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 LOF 38996030 crouchMolecularSubclustersFollicular2022
KLHL6 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 LOF 29695787 crouchMolecularSubclustersFollicular2022
KMT2D 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 26366712 crouchMolecularSubclustersFollicular2022
MAP2K1 1 louissaintPediatrictypeNodalFollicular2016 27325104 GOF 28533310 schmidtMutationsMAP2K1Are2017
MEF2B 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 NEO 23974956; 26245647 crouchMolecularSubclustersFollicular2022
MYC 1 TRUE rossiAberrantSomaticHypermutation2006 17018394 GOF 38565249 crouchMolecularSubclustersFollicular2022
PIM1 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 GOF 27904766 crouchMolecularSubclustersFollicular2022
POU2AF1 1 krysiakRecurrentSomaticMutations2017 28064239 crouchMolecularSubclustersFollicular2022
POU2F2 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 26993806 crouchMolecularSubclustersFollicular2022
RRAGC 1 okosunRecurrentMTORC1activatingRRAGC2016 26691987 GOF 26691987 drevalGeneticSubdivisionsFollicular2023
SGK1 1 TRUE morinFrequentMutationHistonemodifying2011 21796119 GOF 33988691 crouchMolecularSubclustersFollicular2022
SMARCA4 1 krysiakRecurrentSomaticMutations2017 28064239 LOF 33144586 crouchMolecularSubclustersFollicular2022
SOCS1 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 LOF 15572583 crouchMolecularSubclustersFollicular2022
STAT6 1 yildizActivatingSTAT6Mutations2015 25428220 GOF 35851155 crouchMolecularSubclustersFollicular2022
TBL1XR1 1 drevalGeneticSubdivisionsFollicular2023 37084389 LOF 32619424 crouchMolecularSubclustersFollicular2022
TMSB4X 1 TRUE drevalGeneticSubdivisionsFollicular2023 37084389 kalmbachNovelInsightsPathogenesis2023
TNFAIP3 1 drevalGeneticSubdivisionsFollicular2023 37084389 LOF 19412164 crouchMolecularSubclustersFollicular2022
TNFRSF14 1 cheungAcquiredTNFRSF14Mutations2010 21796119 crouchMolecularSubclustersFollicular2022
TP53 1 morinFrequentMutationHistonemodifying2011 21796119 LOF 12826609 crouchMolecularSubclustersFollicular2022
VMA21 1 hubschmannMutationalMechanismsShaping2021 33953289 LOF 35287545 kridelHistologicalTransformationProgression2016
IGLL5 1 TRUE russler-germainMutationsAssociatedProgression2023 37493986 kridelHistologicalTransformationProgression2016
IRF4 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
ABL2 2 russler-germainMutationsAssociatedProgression2023 37563306
ACTG1 2 TRUE hubschmannMutationalMechanismsShaping2021 33953289
ATP6V1A 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
BTG1 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
BTG2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
CD70 2 russler-germainMutationsAssociatedProgression2023 37493986
CD79B 2 drevalGeneticSubdivisionsFollicular2023 37084389
CDC42BPB 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
CILP 2 russler-germainMutationsAssociatedProgression2023 37493986
CPNE8 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
CXCR4 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
CYP2A6 2 russler-germainMutationsAssociatedProgression2023 37493986
NEB 2 maSubtypespecificCooccurringGenetic2022 33792219
DDX3X 2 drevalGeneticSubdivisionsFollicular2023 37084389
DHX15 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
TPTE 2 maSubtypespecificCooccurringGenetic2022 33792219
DUSP2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
EGR1 2 krysiakRecurrentSomaticMutations2017 28064239
FZR1 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
GBP7 2 russler-germainMutationsAssociatedProgression2023 37563306
RHOA 2 maSubtypespecificCooccurringGenetic2022 33792219
GRM6 2 russler-germainMutationsAssociatedProgression2023 37493986
HIST1H2BD 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H2BM 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
TBC1D3F 2 maSubtypespecificCooccurringGenetic2022 33792219
HIST1H3G 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
HIST1H3I 2 TRUE krysiakRecurrentSomaticMutations2017 28064239
ITPKB 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
JUP 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
KIR3DL1 2 russler-germainMutationsAssociatedProgression2023 37563306
KLF2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
LAPTM5 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
LTB 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
MAGEC1 2 russler-germainMutationsAssociatedProgression2023 37563306
MAP7D1 2 russler-germainMutationsAssociatedProgression2023 37563306
MEF2C 2 TRUE laurentFollicularLymphomaComprises2024 NA
MGEA5 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
MKI67 2 russler-germainMutationsAssociatedProgression2023 37493986
MYCBP2 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
MYD88 2 drevalGeneticSubdivisionsFollicular2023 37084389
NFKBIA 2 russler-germainMutationsAssociatedProgression2023 37493986
OR8H2 2 russler-germainMutationsAssociatedProgression2023 37493986
P2RY8 2 drevalGeneticSubdivisionsFollicular2023 37084389
PDS5B 2 PASS 3 hubschmannMutationalMechanismsShaping2021 33953289
PPP4C 2 PASS 4 hubschmannMutationalMechanismsShaping2021 33953289
PRKDC 2 hubschmannMutationalMechanismsShaping2021 33953289
PTPRD 2 drevalGeneticSubdivisionsFollicular2023 37084389
PZP 2 russler-germainMutationsAssociatedProgression2023 37493986
RBM6 2 hubschmannMutationalMechanismsShaping2021 33953289
S1PR2 2 TRUE drevalGeneticSubdivisionsFollicular2023 37084389
SHROOM3 2 russler-germainMutationsAssociatedProgression2023 37493986
SRRM2 2 russler-germainMutationsAssociatedProgression2023 37493986
STAB2 2 russler-germainMutationsAssociatedProgression2023 37493986
TMEM30A 2 morinFrequentMutationHistonemodifying2011 21796119
TPP1 2 hubschmannMutationalMechanismsShaping2021 33953289
XIRP2 2 russler-germainMutationsAssociatedProgression2023 37493986
ZNF608 2 krysiakRecurrentSomaticMutations2017 28064239

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