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didn't edit this in excel
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@kmcoyle
kmcoyle committed Aug 9, 2024
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Showing 1 changed file with 82 additions and 82 deletions.
164 changes: 82 additions & 82 deletions resources/curated/dlbcl_genes.tsv
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Gene Tier aSHM QC Mean variant quality citekey LymphGen PMID MutationEffect Mutation-PMID
ACTB 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
ACTG1 1 TRUE NA fanComprehensiveCharacterizationDriver2020b FALSE 33953289
ARID1A 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937
ATM 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567
B2M 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
BCL10 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
ARID1A 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 LOF 38458187
ATM 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 11756177
B2M 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 22137796
BCL10 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 GOF 35658124
BCL2 1 TRUE NA tanakaFrequentIncidenceSomatic1992 TRUE 1339299
BCL6 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
BCL7A 1 TRUE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
BCL6 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 12504096
BCL7A 1 TRUE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 32576963
BIRC6 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567
BRAF 1 FALSE NA tiacciBRAFMutationsHairycell2011a FALSE 22343534
BTG1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
BRAF 1 FALSE NA tiacciBRAFMutationsHairycell2011a FALSE 22343534 LOF 15035987
BTG1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 33021411
BTG2 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
BTK 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 28327945
CARD11 1 FALSE NA lenzOncogenicCARD11Mutations2008 FALSE 18323416
CCND3 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
CD58 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
CD70 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
CD79B 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
BTK 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a FALSE 28327945 LOF 33419778
CARD11 1 FALSE NA lenzOncogenicCARD11Mutations2008 FALSE 18323416 GOF 18323416
CCND3 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 GOF 22885699
CD58 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 22137796
CD70 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 36471481
CD79B 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 GOF 29669863
CD83 1 TRUE NA morinMutationalStructuralAnalysis2013 TRUE 23699601
CDKN2A 1 FALSE NA morinMutationalStructuralAnalysis2013 TRUE 23699601
CIITA 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
CREBBP 1 FALSE NA pasqualucciInactivatingMutationsAcetyltransferase2011a TRUE 21390126
CXCR4 1 TRUE NA khodabakhshiRecurrentTargetsAberrant2012 FALSE 23131835
DDX3X 1 FALSE NA reddyGeneticFunctionalDrivers2017 TRUE
DTX1 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937
CDKN2A 1 FALSE NA morinMutationalStructuralAnalysis2013 TRUE 23699601 LOF 19260062
CIITA 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 26549456
CREBBP 1 FALSE NA pasqualucciInactivatingMutationsAcetyltransferase2011a TRUE 21390126 LOF 33431788
CXCR4 1 TRUE NA khodabakhshiRecurrentTargetsAberrant2012 FALSE 23131835 LOF 36089616
DDX3X 1 FALSE NA reddyGeneticFunctionalDrivers2017 TRUE LOF 34437837
DTX1 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 LOF 28183850
DUSP2 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
EBF1 1 TRUE NA bohleRoleEarlyBcell2013 FALSE 23174882
EBF1 1 TRUE NA bohleRoleEarlyBcell2013 FALSE 23174882 LOF 28692033
EEF1A1 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 33953289
EP300 1 FALSE NA pasqualucciInactivatingMutationsAcetyltransferase2011a TRUE 21390126
EP300 1 FALSE NA pasqualucciInactivatingMutationsAcetyltransferase2011a TRUE 21390126 LOF 10700188
ETS1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
ETV6 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
EZH2 1 FALSE NA NA morinSomaticMutationsAltering2010a TRUE 20081860 GOF
FAS 1 FALSE NA schollMutationsRegionFAS2007 FALSE 17487740
FBXO11 1 FALSE NA arthurGenomewideDiscoverySomatic2018 FALSE 33953289
FBXW7 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937
FOXO1 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
GNA13 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
GNAI2 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601
ETV6 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 24997145
EZH2 1 FALSE NA NA morinSomaticMutationsAltering2010a TRUE 20081860 GOF 21078963
FAS 1 FALSE NA schollMutationsRegionFAS2007 FALSE 17487740 LOF 20935634
FBXO11 1 FALSE NA arthurGenomewideDiscoverySomatic2018 FALSE 33953289 LOF 22113614
FBXW7 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 LOF 32350066
FOXO1 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 GOF 23460611
GNA13 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 26616858
GNAI2 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601 GOF 23699601
GRB2 1 FALSE NA pasqualucciAnalysisCodingGenome2011 FALSE 21804550
GRHPR 1 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 30275490
HIST1H1B 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
Expand All @@ -50,77 +50,77 @@ HIST1H2BC 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534
HIST1H2BK 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937
HIST1H3B 1 TRUE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534
HIST2H2BE 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29641966
HLA-A 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
HLA-B 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
HLA-C 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
HLA-DMB 1 FALSE NA hubschmannMutationalMechanismsShaping2021b FALSE 33953289
HNRNPU 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567
HLA-A 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 34050029
HLA-B 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 34050029
HLA-C 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 LOF 34050029
HLA-DMB 1 FALSE NA hubschmannMutationalMechanismsShaping2021b FALSE 33953289 LOF 7528727
HNRNPU 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 36201743
HVCN1 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
IKZF3 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
IL4R 1 TRUE NA dunsCharacterizationDLBCLPMBL2021b FALSE 33684939
IKZF3 1 FALSE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 GOF 33689703
IL4R 1 TRUE NA dunsCharacterizationDLBCLPMBL2021b FALSE 33684939 GOF 29467182
IRF4 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
IRF8 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
ITPKB 1 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966
IRF8 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 38996030
ITPKB 1 TRUE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966 LOF 29650799
JUNB 1 FALSE PASS 3 lohrDiscoveryPrioritizationSomatic2012a TRUE 28985567
KLF2 1 TRUE NA pasqualucciAnalysisCodingGenome2011 TRUE 21804550
KLHL14 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937
KLHL6 1 TRUE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119
KLHL14 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 LOF 32127472
KLHL6 1 TRUE NA morinFrequentMutationHistonemodifying2011 FALSE 21796119 LOF 29695787
KMT2C 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937
KMT2D 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
KRAS 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534
KMT2D 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 26366712
KRAS 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 GOF 9219684
LRRN3 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937
LTB 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
MEF2B 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
MEF2B 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 NEO 23974956; 26245647
MEF2C 1 TRUE NA hubschmannMutationalMechanismsShaping2021b FALSE 30275490
MGA 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937
MIR142 1 TRUE NA kwanhianMicroRNA142Mutated202012b FALSE 23342264
MGA 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937 LOF 23039309
MIR142 1 TRUE NA kwanhianMicroRNA142Mutated202012b FALSE 23342264 LOF 29724719
MPEG1 1 FALSE NA morinMutationalStructuralAnalysis2013 TRUE 23699601
MS4A1 1 TRUE NA rushtonGeneticEvolutionaryPatterns2020 FALSE 32589730
MTOR 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937
MYC 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a FALSE NA
MYD88 1 FALSE NA ngoOncogenicallyActiveMYD882011a TRUE 21179087
NFKBIA 1 FALSE NA thomasMutationalAnalysisIkappaBalpha2004 TRUE 15198731
NFKBIE 1 FALSE NA morinGeneticLandscapesRelapsed2016 FALSE 26647218
NFKBIZ 1 TRUE NA morinGeneticLandscapesRelapsed2016 FALSE 26647218
MS4A1 1 TRUE NA rushtonGeneticEvolutionaryPatterns2020 FALSE 32589730 LOF 32589730
MTOR 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 GOF 24631838
MYC 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a FALSE NA GOF 38565249
MYD88 1 FALSE NA ngoOncogenicallyActiveMYD882011a TRUE 21179087 GOF 21179087
NFKBIA 1 FALSE NA thomasMutationalAnalysisIkappaBalpha2004 TRUE 15198731 LOF 10637284
NFKBIE 1 FALSE NA morinGeneticLandscapesRelapsed2016 FALSE 26647218 LOF 25987724
NFKBIZ 1 TRUE NA morinGeneticLandscapesRelapsed2016 FALSE 26647218 GOF 30275490
NOL9 1 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966
NOTCH1 1 FALSE NA pasqualucciAnalysisCodingGenome2011 TRUE 21804550
NOTCH2 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937
NOTCH1 1 FALSE NA pasqualucciAnalysisCodingGenome2011 TRUE 21804550 GOF 29045844
NOTCH2 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937 GOF 19445024
OSBPL10 1 TRUE NA zhangGeneticHeterogeneityDiffuse2013 TRUE 23292937
P2RY8 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534
PIM1 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a TRUE 11460166
P2RY8 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 LOF 25274307
PIM1 1 TRUE NA pasqualucciHypermutationMultipleProtooncogenes2001a TRUE 11460166 GOF 27904766
PIM2 1 TRUE NA reddyGeneticFunctionalDrivers2017 TRUE 30275490
POU2AF1 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
POU2F2 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534
PRDM1 1 FALSE NA pasqualucciInactivationPRDM1BLIMP12006a TRUE NA
PTEN 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE
PTPN6 1 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567
RB1 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601
RFX7 1 FALSE NA NA arthurGenomewideDiscoverySomatic2018 FALSE NA
RHOA 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937
RRAGC 1 FALSE NA okosunRecurrentMTORC1activatingRRAGC2016a FALSE 26691987
S1PR2 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
SETD1B 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945
SF3B1 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE
SGK1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
POU2AF1 1 TRUE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 LOF 30802265
POU2F2 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a FALSE 22343534 LOF 26993806
PRDM1 1 FALSE NA pasqualucciInactivationPRDM1BLIMP12006a TRUE NA LOF 16492805
PTEN 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE LOF 23840064
PTPN6 1 FALSE PASS 3 reddyGeneticFunctionalDrivers2017 FALSE 28985567 LOF 26565811
RB1 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601 LOF 17332242
RFX7 1 FALSE NA NA arthurGenomewideDiscoverySomatic2018 FALSE NA LOF 30926791
RHOA 1 FALSE NA zhangGeneticHeterogeneityDiffuse2013 FALSE 23292937 LOF 26616858
RRAGC 1 FALSE NA okosunRecurrentMTORC1activatingRRAGC2016a FALSE 26691987 GOF 26691987
S1PR2 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 25274307
SETD1B 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945 LOF 21796119
SF3B1 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE NEO 23160465
SGK1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 GOF 33988691
SIN3A 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
SMARCA4 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 22343534
SOCS1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
SMARCA4 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 22343534 LOF 33144586
SOCS1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 15572583
SPEN 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945
STAT3 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 22343534
STAT6 1 FALSE NA yildizActivatingSTAT6Mutations2015c TRUE 25428220
STAT3 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 22343534 GOF 31861597
STAT6 1 FALSE NA yildizActivatingSTAT6Mutations2015c TRUE 25428220 GOF 35851155
TAF1 1 FALSE NA morinMutationalStructuralAnalysis2013 FALSE 23699601
TBL1XR1 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
TET2 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945
TMEM30A 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
TBL1XR1 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534 LOF 32619424
TET2 1 FALSE NA albuquerqueEnhancingKnowledgeDiscovery2017a TRUE 28327945 LOF 23831920
TMEM30A 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 32094924
TMSB4X 1 TRUE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937
TNFAIP3 1 FALSE NA compagnoMutationsMultipleGenes2009a TRUE 19412164
TNFRSF14 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
TNFAIP3 1 FALSE NA compagnoMutationsMultipleGenes2009a TRUE 19412164 LOF 19412164
TNFRSF14 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119 LOF 21796119
TOX 1 FALSE NA reddyGeneticFunctionalDrivers2017 TRUE 28985567
TP53 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 22343534 LOF
TP53 1 FALSE NA morinFrequentMutationHistonemodifying2011 TRUE 22343534 LOF 12826609
UBE2A 1 FALSE NA lohrDiscoveryPrioritizationSomatic2012a TRUE 22343534
WEE1 1 FALSE NA schmitzGeneticsPathogenesisDiffuse2018a TRUE 29641966
XPO1 1 FALSE NA mareschalWholeExomeSequencing2016 FALSE 26608593
ZC3H12A 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087
XPO1 1 FALSE NA mareschalWholeExomeSequencing2016 FALSE 26608593 NEO 33007990
ZC3H12A 1 FALSE NA chapuyMolecularSubtypesDiffuse2018b FALSE 29713087 LOF 19747262
ZFP36L1 1 TRUE NA morinFrequentMutationHistonemodifying2011 TRUE 21796119
ZNF292 1 FALSE NA reddyGeneticFunctionalDrivers2017 FALSE 23292937
ZNF608 1 FALSE NA NA morinMutationalStructuralAnalysis2013 FALSE 23292937
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