---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                           |
|:------:|:----:|--------------------------------------|
|![BL](images/icons/BL_tier2.png)    |2   |relevance in BL not firmly established[@burkhardtClinicalRelevanceMolecular2022]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

### BL

[[include:BL_ADAMTS5.md]]

## Mutation pattern and selective pressure estimates

[[include:dnds_ADAMTS5.md]]


[[include:browser_ADAMTS5.md]]

## Expression
![](images/gene_expression/ADAMTS5_by_pathology.svg)
<!-- ORIGIN: burkhardtClinicalRelevanceMolecular2022b -->
<!-- BL: burkhardtClinicalRelevanceMolecular2022b -->

[[include:mermaid_ADAMTS5.md]]

## References