---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                           |
|:------:|:----:|--------------------------------------|
|![BL](images/icons/BL_tier2.png)    |2   |relevance in BL not firmly established[@muppidiLossSignalingGa132014]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source               |frequency (%)|
|:------:|:---------------------:|:-------------:|
|BL    |GAMBL genomes+capture|3.93         |
|BL    |Thomas cohort        |2.00         |
|BL    |Panea cohort         |  NA         |

## Mutation pattern and selective pressure estimates

[[include:dnds_ARHGEF1.md]]



[[include:browser_ARHGEF1.md]]

## Expression
![](images/gene_expression/ARHGEF1_by_pathology.svg)

<!-- ORIGIN: muppidiLossSignalingGa132014b -->
<!-- BL: muppidiLossSignalingGa132014b -->

[[include:mermaid_ARHGEF1.md]]

## References