---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description            |
|:------:|:----:|-----------------------|
|![FL](images/icons/FL_tier1.png)    |1   |high-confidence FL gene[@okosunRecurrentMTORC1activatingRRAGC2016]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

[[include:FL_ATP6V1B2.md]]

## Mutation pattern and selective pressure estimates

[[include:dnds_ATP6V1B2.md]]

## ATP6V1B2 Hotspots

| Chromosome |Coordinate (hg19) | ref>alt | HGVSp | 
 | :---:| :---: | :--: | :---: |
| chr8 | 20074768 | G>A | R400Q |

[[include:browser_ATP6V1B2.md]]

## Expression
![](images/gene_expression/ATP6V1B2_by_pathology.svg)
<!-- ORIGIN: okosunRecurrentMTORC1activatingRRAGC2016a -->
<!-- FL: okosunRecurrentMTORC1activatingRRAGC2016a -->

[[include:mermaid_ATP6V1B2.md]]

## References