--- bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true --- [[_TOC_]] ## Overview Due to [minimal support](C6orf27#representative-mutation) in the original primary data and very few mutations reported in subsequent studies, this gene is very unlikely to be relevant in BL. ## Relevance tier by entity |Entity|Tier|Description | |:------:|:----:|--------------------------------------| |![BL](images/icons/BL_tier2.png) |3 |Retired, Failed QC[@loveGeneticLandscapeMutations2012]| ## Warnings <> ## Mutation incidence in large patient cohorts (GAMBL reanalysis) |Entity|source |frequency (%)| |:------:|:---------------------:|:-------------:| |BL |GAMBL genomes+capture|NA | |BL |Thomas cohort |NA | |BL |Panea cohort |NA | ## Mutation pattern and selective pressure estimates | [[include:browser_C6orf27.md]]