---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]



## Relevance tier by entity

|Entity|Tier|Description            |
|:------:|:----:|-----------------------|
|![BL](images/icons/BL_tier1.png)    |2   |low-confidence BL gene[@paneaWholeGenomeLandscape2019]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source               |frequency (%)|
|:------:|:---------------------:|:-------------:|
|BL    |GAMBL genomes+capture|4.85         |
|BL    |Thomas cohort        |5.10         |
|BL    |Panea cohort         |6.90         |

## Mutation pattern and selective pressure estimates

[[include:dnds_EIF4A1.md]]


[[include:browser_EIF4A1.md]]

## Expression
![](images/gene_expression/EIF4A1_by_pathology.svg)
<!-- ORIGIN: paneaWholeGenomeLandscape2019 -->
<!-- BL: paneaWholeGenomeLandscape2019 -->

[[include:mermaid_EIF4A1.md]]

## References