---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
  @hubschmannMutationalMechanismsShaping2021, 
---
[[_TOC_]]

## Overview

Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]


## Relevance tier by entity

[[include:tables/table1_FZR1.md]]

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source       |frequency (%)|
|:------:|:-------------:|:-------------:|
|FL    |GAMBL genomes|1.15         |

## Mutation pattern and selective pressure estimates

[[include:tables/dnds_FZR1.md]]

[[include:tables/browser_FZR1.md]]

## Expression
![](images/gene_expression/FZR1_by_pathology.svg)

## All Mutations

[SP194077](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP194077.html)
[SP193650](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP193650.html)

[[include:tables/mermaid_FZR1.md]]

## References


<!-- ORIGIN: hubschmannMutationalMechanismsShaping2021b -->
<!-- FL: hubschmannMutationalMechanismsShaping2021b -->