---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                              |
|:------:|:----:|-----------------------------------------|
|![DLBCL](images/icons/DLBCL_tier2.png) |2   |relevance in DLBCL not firmly established[@schmitzGeneticsPathogenesisDiffuse2018]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |1.34         |
|DLBCL |Schmitz cohort|1.91         |
|DLBCL |Reddy cohort  |2.20         |
|DLBCL |Chapuy cohort |0.85         |

## Mutation pattern and selective pressure estimates

[[include:dnds_GPC5.md]]




[[include:browser_GPC5.md]]

## Expression
![](images/gene_expression/GPC5_by_pathology.svg)
<!-- ORIGIN: schmitzGeneticsPathogenesisDiffuse2018a -->
<!-- DLBCL: schmitzGeneticsPathogenesisDiffuse2018a -->

[[include:mermaid_GPC5.md]]

## References