---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                            |
|:------:|:----:|---------------------------------------|
|![MCL](images/icons/MCL_tier2.png)   |2   |relevance in MCL not firmly established[@zhangGenomicLandscapeMantle2014]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source       |frequency (%)|
|:------:|:-------------:|:-------------:|
|MCL   |GAMBL genomes|0.47         |

## Mutation pattern and selective pressure estimates

|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|
|:------:|:----:|:---------------------:|:----------------:|:----------------:|
|BL    |No  |No                   |0.437           |4.209           |
|DLBCL |No  |No                   |0.961           |0.000           |
|FL    |No  |No                   |0.618           |0.000           |




[[include:browser_GRIN2A.md]]

## Expression
![](images/gene_expression/GRIN2A_by_pathology.svg)
<!-- ORIGIN: zhangGenomicLandscapeMantle2014 -->
<!-- MCL: zhangGenomicLandscapeMantle2014 -->

[[include:mermaid_GRIN2A.md]]

## References