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HIST1H3D

rdmorin edited this page Jun 20, 2024 · 17 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

HIST1H3D

History

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timeline
    title Publication timing
      2019-09-26 : Panea : BL
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Relevance tier by entity

Entity Tier Description
BL 2 relevance in BL not firmly established[@paneaWholeGenomeLandscape2019]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
BL GAMBL genomes+capture 2.31
BL Thomas cohort 1.70
BL Panea cohort 3.00

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 2.566 0
DLBCL No No 2.153 0
FL No No 0.000 0

HIST1H3D Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr6 26197218 G>C S87R
chr6 26197219 C>G S87T
chr6 26197219 C>T S87N

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

Representative Mutations

BL1

Rating ★ ★ ★ ☆ ☆

Rating ★ ★ ★ ☆ ☆

References

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