KRAS
KRAS mutations are rare but occur in some cases of DLBCL.1 These often affect the most common KRAS hotspot sites that are mutated in other solid cancers (G12 and G13).
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timeline
title Publication timing
2012-03-06 : Lohr : DLBCL
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012] |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 27.314 | 0 |
| DLBCL | No | No | 5.336 | 0 |
| FL | No | No | 9.959 | 0 |
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr12 | 25398285 | C>A | G12C |
| chr12 | 25398284 | C>T | G12D |
| chr12 | 25398284 | C>A | G12V |
| chr12 | 25398282 | C>A | G13C |
| chr12 | 25398281 | C>T | G13D |
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
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