KRAS
bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @lohrDiscoveryPrioritizationSomatic2012,
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KRAS mutations are rare but occur in some cases of DLBCL.[@lohrDiscoveryPrioritizationSomatic2012] These often affect the most common KRAS hotspot sites that are mutated in other solid cancers (G12 and G13).
Driver mutations affecting this gene in DLBCL have been experimentally demonstrated to cause a gain of function (GOF).[@scheffzekRasRasGAPComplexStructural1997]
| Chromosome | Coordinate (hg19) | ref>alt | HGVSp |
|---|---|---|---|
| chr12 | 25398285 | C>A | G12C |
| chr12 | 25398284 | C>T | G12D |
| chr12 | 25398284 | C>A | G12V |
| chr12 | 25398282 | C>A | G13C |
| chr12 | 25398281 | C>T | G13D |
include:tables/browser_KRAS.md
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