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rdmorin edited this page Apr 19, 2024 · 30 revisions

[LTB]

Mutation tier

Entity Tier
BL 2
DLBCL 1
FL 1

Mutation incidence

Entity study frequency (%)
BL GAMBL genomes+capture 3.00
BL Thomas cohort 3.00
BL Panea cohort 5.90
DLBCL GAMBL genomes 11.30
DLBCL Schmitz cohort 8.50
DLBCL Reddy cohort NA
DLBCL Chapuy cohort 9.80
FL GAMBL genomes 8.78

Mutation pattern

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL Yes No 4.330 0.000
DLBCL Yes No 2.261 10.402
FL Yes No 5.259 35.735

aSHM regions

chr_name hg19_start hg19_end region regulatory_comment
chr6 31548325 31550717 intron-1 enhancer

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