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rdmorin edited this page Dec 28, 2024 · 19 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true nocite: | @hubschmannMutationalMechanismsShaping2021,

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Overview

Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]

Relevance tier by entity

Entity Tier Description
FL 2 relevance in FL not firmly established[@hubschmannMutationalMechanismsShaping2021]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
FL GAMBL genomes 1.85

Mutation pattern and selective pressure estimates

Entity aSHM Significant selection dN/dS (missense) dN/dS (nonsense)
BL No No 1.383 0
DLBCL No No 2.152 0
FL No No 3.398 0

include:browser_MGEA5.md

Expression

All Mutations

SP193655 SP116618 SP116649

include:mermaid_MGEA5.md

References

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