MPEG1
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Mutations in MPEG1 have been described in DLBCL[@morinMutationalStructuralAnalysis2013] with the overall rate of mutations somewhat variable across studies. MPEG1 is one of a number of genes affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus. Coding and non-coding MPEG1 mutations are a feature of the MCD genetic subgroup of DLBCL.
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence MZL gene |
 |
1 | high-confidence DLBCL gene[@morinMutationalStructuralAnalysis2013; @schmitzGeneticsPathogenesisDiffuse2018] |
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