---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                              |
|:------:|:----:|-----------------------------------------|
|![DLBCL](images/icons/DLBCL_tier2.png) |2   |relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |1.91         |
|DLBCL |Schmitz cohort|2.55         |
|DLBCL |Reddy cohort  |2.60         |
|DLBCL |Chapuy cohort |2.56         |

## Mutation pattern and selective pressure estimates

[[include:dnds_MSH6.md]]




[[include:browser_MSH6.md]]

## Expression
![](images/gene_expression/MSH6_by_pathology.svg)
<!-- ORIGIN: reddyGeneticFunctionalDrivers2017 -->
<!-- DLBCL: reddyGeneticFunctionalDrivers2017 -->

[[include:mermaid_MSH6.md]]

## References