---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]



## Relevance tier by entity

|Entity|Tier|Description                              |
|:------:|:----:|-----------------------------------------|
|![PMBL](images/icons/PMBL_tier2.png)|2|relevance in PMBL/cHL/GZL not firmly established[@deschGenotypingCirculatingTumor2020]|
|![DLBCL](images/icons/DLBCL_tier2.png) |3   |Retired, Failed QC|

## Warnings

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |0.57         |
|DLBCL |Schmitz cohort|2.13         |
|DLBCL |Reddy cohort  |1.10         |
|DLBCL |Chapuy cohort |0.85         |

## Mutation pattern and selective pressure estimates

[[include:dnds_MYB.md]]




[[include:browser_MYB.md]]

## Expression
![](images/gene_expression/MYB_by_pathology.svg)
<!-- ORIGIN: reddyGeneticFunctionalDrivers2017 -->
<!-- DLBCL: reddyGeneticFunctionalDrivers2017 -->
<!-- PMBL: deschGenotypingCirculatingTumor2020 -->

## All Mutations

[Reddy_2120T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2120T.html)
[Reddy_2137T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2137T.html)
[Reddy_2140T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2140T.html)
[Reddy_2190T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2190T.html)
[Reddy_2450T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2450T.html)
[Reddy_2680T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2680T.html)
[Reddy_2895T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2895T.html)
[Reddy_2935T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_2935T.html)
[Reddy_3394T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3394T.html)
[Reddy_3485T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3485T.html)
[Reddy_3755T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3755T.html)
[Reddy_3766T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3766T.html)
[Reddy_3779T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3779T.html)
[Reddy_3783T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3783T.html)
[Reddy_3846T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3846T.html)
[Reddy_3852T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3852T.html)
[Reddy_3948T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3948T.html)
[Reddy_3961T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3961T.html)
[Reddy_3978T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3978T.html)
[Reddy_3990T](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Reddy/igv_reports/Reddy_3990T.html)

[[include:mermaid_MYB.md]]

## References