MYOM2
The prevalence of MYOM2 mutations in DLBCL varies across studies. The role of these mutations in lymphomagenesis has not been thoroughly explored.
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timeline
title Publication timing
2011-07-31 : Pasqualucci : DLBCL
| Entity | Tier | Description |
|---|---|---|
 |
1 | high-confidence DLBCL gene |
| Entity | source | frequency (%) |
|---|---|---|
| DLBCL | GAMBL genomes | 3.25 |
| DLBCL | Schmitz cohort | 8.09 |
| DLBCL | Reddy cohort | 3.20 |
| DLBCL | Chapuy cohort | 4.27 |
| Entity | aSHM | Significant selection | dN/dS (missense) | dN/dS (nonsense) |
|---|---|---|---|---|
| BL | No | No | 2.021 | 0.000 |
| DLBCL | No | No | 0.893 | 2.648 |
| FL | No | No | 0.649 | 12.057 |
Note
First described in DLBCL in 2011 by Pasqualucci L
View coding variants in ProteinPaint hg19 or hg38
View all variants in GenomePaint hg19 or hg38
- Pasqualucci L, Trifonov V, Fabbri G, Ma J, Rossi D, Chiarenza A, Wells VA, Grunn A, Messina M, Elliot O, Chan J, Bhagat G, Chadburn A, Gaidano G, Mullighan CG, Rabadan R, Dalla-Favera R. Analysis of the coding genome of diffuse large B-cell lymphoma. Nat Genet. 2011 Jul 31;43(9):830–837. PMCID: PMC3297422
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