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Ryan Morin edited this page Dec 16, 2024 · 20 revisions

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

[[TOC]]

Relevance tier by entity

Entity Tier Description
MZL 1 high-confidence MZL gene
PMBL 1 high-confidence PMBL/cHL/GZL gene
DLBCL 2 relevance in DLBCL not firmly established[@lohrDiscoveryPrioritizationSomatic2012]
FL 1 high-confidence FL gene

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity source frequency (%)
DLBCL GAMBL genomes 16.44
DLBCL Schmitz cohort 21.28
DLBCL Reddy cohort 15.12
DLBCL Chapuy cohort 23.08
FL GAMBL genomes 9.24

Mutation pattern and selective pressure estimates

include:dnds_PCLO.md

PCLO Hotspots

Chromosome Coordinate (hg19) ref>alt HGVSp
chr7 82585303 G>T L1656I
chr7 82585302 A>G L1656P
chr7 82544727 T>C K4192R

include:browser_PCLO.md

Expression

include:mermaid_PCLO.md

References

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