PIK3CD

---

bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

[[TOC]]

Relevance tier by entity

Entity	Tier	Description
	2	relevance in DLBCL not firmly established[@zhangGeneticHeterogeneityDiffuse2013]

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	3.82
DLBCL	Schmitz cohort	4.89
DLBCL	Reddy cohort	2.50
DLBCL	Chapuy cohort	2.14

Mutation pattern and selective pressure estimates

include:dnds_PIK3CD.md

PIK3CD Hotspots

Chromosome	Coordinate (hg19)	ref>alt	HGVSp
chr1	9787030	G>A	E1021K
chr1	9787040	G>A	R1024H
chr1	9787043	A>G	E1025G

View coding variants in ProteinPaint hg19 or hg38

View all variants in GenomePaint hg19 or hg38

PIK3CD Expression

All Mutations

Reddy_2141T Reddy_2153T Reddy_2158T Reddy_2161T Reddy_2162T Reddy_2247T Reddy_2263T Reddy_2273T Reddy_2448T Reddy_2449T Reddy_2606T Reddy_2626T Reddy_2632T Reddy_2684T Reddy_2709T Reddy_2719T Reddy_2766T Reddy_2776T Reddy_2777T Reddy_2781T Reddy_2806T Reddy_2815T Reddy_2884T Reddy_2886T Reddy_2899T Reddy_2915T Reddy_2934T Reddy_2951T Reddy_2952T Reddy_2995T Reddy_3382T Reddy_3386T Reddy_3396T Reddy_3398T Reddy_3429T Reddy_3431T Reddy_3432T Reddy_3444T Reddy_3447T Reddy_3451T Reddy_3454T Reddy_3458T Reddy_3460T Reddy_3464T Reddy_3496T Reddy_3505T Reddy_3523T Reddy_3528T Reddy_3580T Reddy_3582T Reddy_3597T Reddy_3603T Reddy_3638T Reddy_3662T Reddy_3683T Reddy_3819T Reddy_3900T Reddy_3911T Reddy_3914T Reddy_3927T Reddy_3948T Reddy_3960T Reddy_3974T

include:mermaid_PIK3CD.md

References