---
title: 'Studies'
bibliography: 'morinlab.bib'
---

|Year|Focus|Sequencing Method|Novel genes| Tier 1 (%)|Example gene|Study|
|:-:|:-:|:-:|:-:|:-:|:-:|:-------:|
|1992|BL|Sanger|1|1 (100.0)|MYC|[@johnstonCmycHypermutationBurkitt1992](papers/johnstonCmycHypermutationBurkitt1992.md)|
|1992|DLBCL|Sanger|1|1 (100.0)|BCL2|[@tanakaFrequentIncidenceSomatic1992](papers/tanakaFrequentIncidenceSomatic1992.md)|
|2001|DLBCL|Sanger|4|2 (50.0)|MYC|[@pasqualucciHypermutationMultipleProtooncogenes2001](papers/pasqualucciHypermutationMultipleProtooncogenes2001.md)|
|2004|BL|Sanger|1|1 (100.0)|TP53|[@wildaInactivationARFMDM2p53Pathway2004](papers/wildaInactivationARFMDM2p53Pathway2004.md)|
|2006|DLBCL|Sanger|1|1 (100.0)|PRDM1|[@pasqualucciInactivationPRDM1BLIMP12006](papers/pasqualucciInactivationPRDM1BLIMP12006.md)|
|2006|PMBL|Sanger|2|1 (50.0)|GPR126|[@wenigerMutationsTumorSuppressor2006](papers/wenigerMutationsTumorSuppressor2006.md)|
|2007|DLBCL|Sanger|1|1 (100.0)|FAS|[@schollMutationsRegionFAS2007](papers/schollMutationsRegionFAS2007.md)|
|2008|DLBCL|Sanger|1|1 (100.0)|CARD11|[@lenzOncogenicCARD11Mutations2008](papers/lenzOncogenicCARD11Mutations2008.md)|
|2009|DLBCL|Sanger|1|1 (100.0)|NFKBIA|[@lakeMutationsNFKBIAEncoding2009](papers/lakeMutationsNFKBIAEncoding2009.md)|
|2009|DLBCL|Sanger|1|1 (100.0)|TNFAIP3|[@compagnoMutationsMultipleGenes2009](papers/compagnoMutationsMultipleGenes2009.md)|
|2009|PMBL|Sanger|1|1 (100.0)|STAT6|[@ritzRecurrentMutationsSTAT62009](papers/ritzRecurrentMutationsSTAT62009.md)|
|2009|PMBL|Sanger|1|1 (100.0)|TNFAIP3|[@schmitzTNFAIP3A20Tumor2009](papers/schmitzTNFAIP3A20Tumor2009.md)|
|2010|FL|Sanger|1|1 (100.0)|TNFRSF14|[@cheungAcquiredTNFRSF14Mutations2010](papers/cheungAcquiredTNFRSF14Mutations2010.md)|
|2010|DLBCL|RNA-seq/WGS|1|1 (100.0)|EZH2|[@morinSomaticMutationsAltering2010](papers/morinSomaticMutationsAltering2010.md)|
|2011|DLBCL|RNA-seq/WGS|29|27 (93.1)|B2M|[@morinFrequentMutationHistonemodifying2011](papers/morinFrequentMutationHistonemodifying2011.md)|
|2011|DLBCL|exome|7|3 (42.9)|CD36|[@pasqualucciAnalysisCodingGenome2011](papers/pasqualucciAnalysisCodingGenome2011.md)|
|2011|DLBCL|Sanger|1|1 (100.0)|MYD88|[@ngoOncogenicallyActiveMYD882011](papers/ngoOncogenicallyActiveMYD882011.md)|
|2011|FL|exome|2|2 (100.0)|CREBBP|[@pasqualucciInactivatingMutationsAcetyltransferase2011](papers/pasqualucciInactivatingMutationsAcetyltransferase2011.md)|
|2011|DLBCL|exome/Sanger|1|1 (100.0)|BRAF|[@tiacciBRAFMutationsHairycell2011](papers/tiacciBRAFMutationsHairycell2011.md)|
|2011|MZL|Sanger|5|4 (80.0)|BIRC3|[@rossiAlterationBIRC3Multiple2011](papers/rossiAlterationBIRC3Multiple2011.md)|
|2012|MZL|exome|21|10 (47.6)|ARID1A|[@rossiCodingGenomeSplenic2012](papers/rossiCodingGenomeSplenic2012.md)|
|2012|BL|RNA-seq/WGS/exome|5|5 (100.0)|CCND3|[@richterRecurrentMutationID32012](papers/richterRecurrentMutationID32012.md)|
|2012|DLBCL|Sanger|1|0 (0.0)|MIR142|[@kwanhianMicroRNA142Mutated202012](papers/kwanhianMicroRNA142Mutated202012.md)|
|2012|DLBCL|WGS|1|1 (100.0)|CXCR4|[@khodabakhshiRecurrentTargetsAberrant2012](papers/khodabakhshiRecurrentTargetsAberrant2012.md)|
|2012|PMBL|Array/Sanger|2|2 (100.0)|MAP3K14|[@ottoGeneticLesionsTRAF32012](papers/ottoGeneticLesionsTRAF32012.md)|
|2012|DLBCL|exome|39|18 (46.2)|ACTB|[@lohrDiscoveryPrioritizationSomatic2012](papers/lohrDiscoveryPrioritizationSomatic2012.md)|
|2012|MZL|Panel|2|2 (100.0)|CARD11|[@yanBCRTLRSignaling2012](papers/yanBCRTLRSignaling2012.md)|
|2012|BL|exome|60|3 (5.0)|ACAD9|[@loveGeneticLandscapeMutations2012](papers/loveGeneticLandscapeMutations2012.md)|
|2012|BL|RNA-seq|20|4 (20.0)|C16orf48|[@schmitzBurkittLymphomaPathogenesis2012](papers/schmitzBurkittLymphomaPathogenesis2012.md)|
|2012|MZL|Array/Sanger|1|1 (100.0)|ATM|[@braggioGenomicAnalysisMarginal2012](papers/braggioGenomicAnalysisMarginal2012.md)|
|2013|MCL|WGS/exome|27|11 (40.7)|ABCA3|[@beaLandscapeSomaticMutations2013](papers/beaLandscapeSomaticMutations2013.md)|
|2013|DLBCL|exome|16|8 (50.0)|ARID1A|[@zhangGeneticHeterogeneityDiffuse2013](papers/zhangGeneticHeterogeneityDiffuse2013.md)|
|2013|DLBCL|Sanger|1|1 (100.0)|EBF1|[@bohleRoleEarlyBcell2013](papers/bohleRoleEarlyBcell2013.md)|
|2013|DLBCL|WGS|38|9 (23.7)|ABI3BP|[@morinMutationalStructuralAnalysis2013](papers/morinMutationalStructuralAnalysis2013.md)|
|2013|MZL|exome|8|0 (0.0)|AMOTL1|[@parryWholeExomeSequencing2013](papers/parryWholeExomeSequencing2013.md)|
|2014|MCL|exome|28|2 (7.1)|ANK2|[@zhangGenomicLandscapeMantle2014](papers/zhangGenomicLandscapeMantle2014.md)|
|2014|PMBL|WGS/Sanger|1|1 (100.0)|PTPN1|[@gunawardanaRecurrentSomaticMutations2014](papers/gunawardanaRecurrentSomaticMutations2014.md)|
|2014|BL|Sanger|3|1 (33.3)|ARHGEF1|[@muppidiLossSignalingGa132014](papers/muppidiLossSignalingGa132014.md)|
|2015|BL|RNA-seq|1|0 (0.0)|CCNF|[@abateDistinctViralMutational2015](papers/abateDistinctViralMutational2015.md)|
|2015|DLBCL|Sanger|1|1 (100.0)|STAT6|[@yildizActivatingSTAT6Mutations2015](papers/yildizActivatingSTAT6Mutations2015.md)|
|2015|PMBL|Sanger|1|1 (100.0)|CIITA|[@mottokGenomicAlterationsCIITA2015](papers/mottokGenomicAlterationsCIITA2015.md)|
|2015|PMBL|Sanger|1|1 (100.0)|CD58|[@schneiderAlterationsCD58Gene2015](papers/schneiderAlterationsCD58Gene2015.md)|
|2015|PMBL|exome|29|11 (37.9)|ARIH2|[@reichelFlowSortingExome2015](papers/reichelFlowSortingExome2015.md)|
|2015|DLBCL|Sanger|1|0 (0.0)|MAP2K1|[@shinBRAFV600EMAP2K12015](papers/shinBRAFV600EMAP2K12015.md)|
|2016|MZL|exome|1|1 (100.0)|KLHL6|[@ganapathiGeneticLandscapeDural2016](papers/ganapathiGeneticLandscapeDural2016.md)|
|2016|DLBCL|exome|1|1 (100.0)|XPO1|[@mareschalWholeExomeSequencing2016](papers/mareschalWholeExomeSequencing2016.md)|
|2016|FL|WGS|3|3 (100.0)|ATP6AP1|[@okosunRecurrentMTORC1activatingRRAGC2016](papers/okosunRecurrentMTORC1activatingRRAGC2016.md)|
|2016|PMBL|Sanger|1|1 (100.0)|XPO1|[@jardinRecurrentMutationsExportin2016](papers/jardinRecurrentMutationsExportin2016.md)|
|2016|PMBL|exome/Sanger|1|1 (100.0)|NFKBIE|[@mansouriFrequentNFKBIEDeletions2016](papers/mansouriFrequentNFKBIEDeletions2016.md)|
|2016|FL|exome|1|1 (100.0)|MAP2K1|[@louissaintPediatrictypeNodalFollicular2016](papers/louissaintPediatrictypeNodalFollicular2016.md)|
|2016|MZL|exome/panel|31|8 (25.8)|ABCA13|[@spinaGeneticsNodalMarginal2016](papers/spinaGeneticsNodalMarginal2016.md)|
|2016|MCL|exome|1|1 (100.0)|CARD11|[@wuGeneticHeterogeneityPrimary2016](papers/wuGeneticHeterogeneityPrimary2016.md)|
|2016|DLBCL|exome|2|2 (100.0)|NFKBIE|[@morinGeneticLandscapesRelapsed2016](papers/morinGeneticLandscapesRelapsed2016.md)|
|2017|MZL|panel|2|0 (0.0)|CD9B|[@vandenbrandRecurrentMutationsGenes2017](papers/vandenbrandRecurrentMutationsGenes2017.md)|
|2017|MZL|exome|28|2 (7.1)|ARHGAP20|[@jalladesExomeSequencingIdentifies2017](papers/jalladesExomeSequencingIdentifies2017.md)|
|2017|FL|exome|22|17 (77.3)|ARID1A|[@krysiakRecurrentSomaticMutations2017](papers/krysiakRecurrentSomaticMutations2017.md)|
|2017|DLBCL|exome|3|3 (100.0)|BTK|[@albuquerqueEnhancingKnowledgeDiscovery2017](papers/albuquerqueEnhancingKnowledgeDiscovery2017.md)|
|2017|DLBCL|exome|59|6 (10.2)|ANKRD17|[@reddyGeneticFunctionalDrivers2017](papers/reddyGeneticFunctionalDrivers2017.md)|
|2018|PMBL|exome|10|1 (10.0)|AKAP6|[@tiacciPervasiveMutationsJAKSTAT2018](papers/tiacciPervasiveMutationsJAKSTAT2018.md)|
|2018|DLBCL|exome|19|2 (10.5)|CCL4|[@chapuyMolecularSubtypesDiffuse2018](papers/chapuyMolecularSubtypesDiffuse2018.md)|
|2018|PMBL|Sanger|1|1 (100.0)|IL4R|[@viganoSomaticIL4RMutations2018](papers/viganoSomaticIL4RMutations2018.md)|
|2018|DLBCL|WGS|19|7 (36.8)|AICDA|[@arthurGenomewideDiscoverySomatic2018](papers/arthurGenomewideDiscoverySomatic2018.md)|
|2018|DLBCL|exome|16|7 (43.8)|CXCR5|[@schmitzGeneticsPathogenesisDiffuse2018](papers/schmitzGeneticsPathogenesisDiffuse2018.md)|
|2019|PMBL|exome|7|4 (57.1)|ACTB|[@wienandGenomicAnalysesFlowsorted2019](papers/wienandGenomicAnalysesFlowsorted2019.md)|
|2019|BL|exome|1|0 (0.0)|KMT2C|[@zhouSporadicEndemicBurkitt2019](papers/zhouSporadicEndemicBurkitt2019.md)|
|2019|BL|RNA-seq/exome|39|4 (10.3)|ALPK2|[@paneaWholeGenomeLandscape2019](papers/paneaWholeGenomeLandscape2019.md)|
|2019|BL|WGS|13|9 (69.2)|BACH2|[@grandeGenomewideDiscoverySomatic2019](papers/grandeGenomewideDiscoverySomatic2019.md)|
|2019|PMBL|exome|21|6 (28.6)|CISH|[@mottokIntegrativeGenomicAnalysis2019](papers/mottokIntegrativeGenomicAnalysis2019.md)|
|2020|MCL|WGS|5|3 (60.0)|BCOR|[@nadeuGenomicEpigenomicInsights2020](papers/nadeuGenomicEpigenomicInsights2020.md)|
|2020|FL|panel|1|1 (100.0)|CTSS|[@barariaCathepsinAlterationsInduce2020](papers/barariaCathepsinAlterationsInduce2020.md)|
|2020|DLBCL|exome/panel|1|1 (100.0)|MS4A1|[@rushtonGeneticEvolutionaryPatterns2020](papers/rushtonGeneticEvolutionaryPatterns2020.md)|
|2020|MCL|WGS/exome|7|6 (85.7)|B2M|[@pararajalingamCodingNoncodingDrivers2020](papers/pararajalingamCodingNoncodingDrivers2020.md)|
|2020|PMBL|panel|10|1 (10.0)|ACTG1|[@deschGenotypingCirculatingTumor2020](papers/deschGenotypingCirculatingTumor2020.md)|
|2021|DLBCL|WGS|38|3 (7.9)|ACTG1|[@hubschmannMutationalMechanismsShaping2021](papers/hubschmannMutationalMechanismsShaping2021.md)|
|2021|PMBL|exome|11|5 (45.5)|ABCA13|[@sarkozyMutationalLandscapeGray2021](papers/sarkozyMutationalLandscapeGray2021.md)|
|2021|PMBL|exome|14|6 (42.9)|BIRC3|[@dunsCharacterizationDLBCLPMBL2021](papers/dunsCharacterizationDLBCLPMBL2021.md)|
|2022|BL|panel|25|0 (0.0)|ADAMTS5|[@burkhardtClinicalRelevanceMolecular2022](papers/burkhardtClinicalRelevanceMolecular2022.md)|
|2023|BL|WGS|6|2 (33.3)|CDKN2C|[@thomasGeneticSubgroupsInform2023](papers/thomasGeneticSubgroupsInform2023.md)|
|2023|FL|exome|20|1 (5.0)|ABL2|[@russler-germainMutationsAssociatedProgression2023](papers/russler-germainMutationsAssociatedProgression2023.md)|
|2023|PMBL|exome|7|2 (28.6)|ARID5B|[@gomezUltraDeepSequencingReveals2023](papers/gomezUltraDeepSequencingReveals2023.md)|

# References