---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
nocite: |
  @hubschmannMutationalMechanismsShaping2021, 
---
[[_TOC_]]

## Overview

Mutations in this gene were first described in DLBCL and FL in 2021 by Hübschmann et al.[@hubschmannMutationalMechanismsShaping2021]


## Relevance tier by entity

[[include:tables/table1_RBM6.md]]

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source       |frequency (%)|
|:------:|:-------------:|:-------------:|
|FL    |GAMBL genomes|0.46         |

## Mutation pattern and selective pressure estimates

[[include:tables/dnds_RBM6.md]]


[[include:tables/browser_RBM6.md]]

## Expression
![](images/gene_expression/RBM6_by_pathology.svg)

## All Mutations

[SP193025](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP193025.html)
[SP59320](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP59320.html)

[[include:tables/mermaid_RBM6.md]]

## References


<!-- ORIGIN: hubschmannMutationalMechanismsShaping2021b -->
<!-- FL: hubschmannMutationalMechanismsShaping2021b -->