---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description               |
|:------:|:----:|--------------------------|
|![DLBCL](images/icons/DLBCL_tier1.png) |1   |high-confidence DLBCL gene[@reddyGeneticFunctionalDrivers2017;@hubschmannMutationalMechanismsShaping2021]|
|![FL](images/icons/FL_tier1.png)    |1   |high-confidence FL gene  [@okosunRecurrentMTORC1activatingRRAGC2016] |

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

[[include:DLBCL_RRAGC.md]]
[[include:FL_RRAGC.md]]

## Mutation pattern and selective pressure estimates

[[include:dnds_RRAGC.md]]

[[include:browser_RRAGC.md]]

## Expression
![](images/gene_expression/RRAGC_by_pathology.svg)
<!-- ORIGIN: okosunRecurrentMTORC1activatingRRAGC2016a -->
<!-- DLBCL: okosunRecurrentMTORC1activatingRRAGC2016a -->

[[include:mermaid_RRAGC.md]]

## References