---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]



## Relevance tier by entity

|Entity|Tier|Description                            |
|:------:|:----:|---------------------------------------|
|![BL](images/icons/BL_tier2.png)    |3   |Retired, Failed QC[@loveGeneticLandscapeMutations2012]|
|![MCL](images/icons/MCL_tier2.png)   |2   |relevance in MCL not firmly established[@zhangGenomicLandscapeMantle2014]|

## Warnings

<<Warn("The variants reported in this gene in BL failed QC")>>

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source               |frequency (%)|
|:------:|:---------------------:|:-------------:|
|BL    |GAMBL genomes+capture|4.16         |
|BL    |Thomas cohort        |  NA         |
|BL    |Panea cohort         |  NA         |
|MCL   |GAMBL genomes        |0.95         |

## Mutation pattern and selective pressure estimates

[[include:dnds_SALL3.md]]




[[include:browser_SALL3.md]]

## Expression
![](images/gene_expression/SALL3_by_pathology.svg)
<!-- ORIGIN: loveGeneticLandscapeMutations2012 -->
<!-- MCL: zhangGenomicLandscapeMantle2014 -->
<!-- BL: loveGeneticLandscapeMutations2012 -->

## Representative Mutations

![](primary/Love_SALL3.svg)
**Rating**
&starf; &starf; &star; &star; &star;

## All Mutations

[1096](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/1096_reports.html)
[475](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/475_reports.html)
[513](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/513_reports.html)
[515](https://www.bcgsc.ca/downloads/morinlab/GAMBL/Love/515_reports.html)

[[include:mermaid_SALL3.md]]

## References