SETD5

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bibliography: 'morinlab.bib' csl: 'NLM.csl' link-citations: true

[[TOC]]

Relevance tier by entity

Entity	Tier	Description
	2	relevance in PMBL/cHL/GZL not firmly established[@tiacciPervasiveMutationsJAKSTAT2018]
	2	relevance in DLBCL not firmly established[@reddyGeneticFunctionalDrivers2017]

Warnings

<<Warn("The variants reported in this gene in DLBCL failed QC")>>

Mutations in this gene were reported to be inflated in the original results according to Dreval K

Mutation incidence in large patient cohorts (GAMBL reanalysis)

Entity	source	frequency (%)
DLBCL	GAMBL genomes	2.49
DLBCL	Schmitz cohort	5.32
DLBCL	Reddy cohort	3.20
DLBCL	Chapuy cohort	2.14

Mutation pattern and selective pressure estimates

include:dnds_SETD5.md

include:browser_SETD5.md

Expression

Representative Mutations

Rating ★ ★ ★ ★ ★

Rating ★ ★ ☆ ☆ ☆

All Mutations

Reddy_2084T Reddy_2130T Reddy_2154T Reddy_2226T Reddy_2249T Reddy_2306T Reddy_2478T Reddy_2522T Reddy_2539T Reddy_2547T Reddy_2559T Reddy_2561T Reddy_2636T Reddy_2655T Reddy_2671T Reddy_2681T Reddy_2691T Reddy_2905T Reddy_2912T Reddy_2949T Reddy_2956T Reddy_2957T Reddy_3389T Reddy_3399T Reddy_3405T Reddy_3489T Reddy_3597T Reddy_3643T Reddy_3692T Reddy_3727T Reddy_3748T Reddy_3754T Reddy_3834T Reddy_3859T Reddy_3898T Reddy_3923T Reddy_3937T Reddy_3960T Reddy_3973T Reddy_3984T Reddy_3992T Reddy_3995T Reddy_695T

include:mermaid_SETD5.md

References