---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                              |
|:------:|:----:|-----------------------------------------|
|![DLBCL](images/icons/DLBCL_tier2.png) |2   |relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |0.76         |
|DLBCL |Schmitz cohort|1.70         |
|DLBCL |Reddy cohort  |1.40         |
|DLBCL |Chapuy cohort |0.85         |

## Mutation pattern and selective pressure estimates

[[include:dnds_SLC34A2.md]]


[[include:browser_SLC34A2.md]]

## Expression
![](images/gene_expression/SLC34A2_by_pathology.svg)
<!-- ORIGIN: hubschmannMutationalMechanismsShaping2021b -->
<!-- DLBCL: hubschmannMutationalMechanismsShaping2021b -->

## All Mutations

[SP116668](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP116668.html)
[SP192997](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP192997.html)
[SP193312](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP193312.html)
[SP194108](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP194108.html)

[[include:mermaid_SLC34A2.md]]

## References