---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                            |
|:------:|:----:|---------------------------------------|
|![MCL](images/icons/MCL_tier2.png)   |2   |relevance in MCL not firmly established[@nadeuGenomicEpigenomicInsights2020]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source       |frequency (%)|
|:------:|:-------------:|:-------------:|
|MCL   |GAMBL genomes|1.9          |

## Mutation pattern and selective pressure estimates

|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|
|:------:|:----:|:---------------------:|:----------------:|:----------------:|
|BL    |No  |No                   |10.709          |0               |
|DLBCL |No  |No                   | 0.000          |0               |
|FL    |No  |No                   |15.559          |0               |




[[include:browser_SMARCB1.md]]

## Expression
![](images/gene_expression/SMARCB1_by_pathology.svg)
<!-- ORIGIN: nadeuGenomicEpigenomicInsights2020a -->
<!-- MCL: nadeuGenomicEpigenomicInsights2020b -->

[[include:mermaid_SMARCB1.md]]

## References