---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description             |
|:------:|:----:|------------------------|
|![MCL](images/icons/MCL_tier1.png)   |1   |high-confidence MCL gene[@beaLandscapeSomaticMutations2013]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source       |frequency (%)|
|:------:|:-------------:|:-------------:|
|MCL   |GAMBL genomes|5.21         |

## Mutation pattern and selective pressure estimates

|Entity|aSHM|Significant selection|dN/dS (missense)|dN/dS (nonsense)|
|:------:|:----:|:---------------------:|:----------------:|:----------------:|
|BL    |No  |No                   |0.000           | 0.000          |
|DLBCL |No  |No                   |0.803           |11.118          |
|FL    |No  |No                   |0.000           | 0.000          |




[[include:browser_SP140.md]]

## Expression
![](images/gene_expression/SP140_by_pathology.svg)
<!-- ORIGIN: beaLandscapeSomaticMutations2013 -->
<!-- MCL: beaLandscapeSomaticMutations2013 -->

[[include:mermaid_SP140.md]]

## References