---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]

## Overview

Mutations in BL were first described by Grande et al.[@grandeGenomewideDiscoverySomatic2019]


## Relevance tier by entity

|Entity|Tier|Description            |
|:------:|:----:|-----------------------|
|![BL](images/icons/BL_tier1.png)    |1   |high-confidence BL gene[@grandeGenomewideDiscoverySomatic2019]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

[[include:DLBCL_TFAP4.md]]
[[include:BL_TFAP4.md]]

## Mutation pattern and selective pressure estimates

[[include:dnds_TFAP4.md]]

[[include:browser_TFAP4.md]]

## Expression
![](images/gene_expression/TFAP4_by_pathology.svg)

[[include:mermaid_TFAP4.md]]

## References

<!-- ORIGIN: grandeGenomewideDiscoverySomatic2019 -->
<!-- BL: grandeGenomewideDiscoverySomatic2019 -->