---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description                              |
|:------:|:----:|-----------------------------------------|
|![DLBCL](images/icons/DLBCL_tier2.png) |2   |relevance in DLBCL not firmly established[@hubschmannMutationalMechanismsShaping2021]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |1.53         |
|DLBCL |Schmitz cohort|2.98         |
|DLBCL |Reddy cohort  |1.80         |
|DLBCL |Chapuy cohort |2.14         |

## Mutation pattern and selective pressure estimates

[[include:dnds_UNC5B.md]]

 
[[include:browser_UNC5B.md]]

## Expression
![](images/gene_expression/UNC5B_by_pathology.svg)
<!-- ORIGIN: hubschmannMutationalMechanismsShaping2021b -->
<!-- DLBCL: hubschmannMutationalMechanismsShaping2021b -->

## All Mutations

[SP193720](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP193720.html)
[SP194143](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP194143.html)
[SP59400](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP59400.html)
[SP59448](https://www.bcgsc.ca/downloads/morinlab/GAMBL/MALY/SP59448.html)

[[include:mermaid_UNC5B.md]]

## References