---
bibliography: 'morinlab.bib'
csl: 'NLM.csl'
link-citations: true
---
[[_TOC_]]


## Relevance tier by entity

|Entity|Tier|Description               |
|:------:|:----:|--------------------------|
|![PMBL](images/icons/PMBL_tier1.png)|1|high-confidence PMBL/cHL/GZL gene|
|![DLBCL](images/icons/DLBCL_tier1.png) |2   |low-confidence DLBCL gene[@lohrDiscoveryPrioritizationSomatic2012]|

## Mutation incidence in large patient cohorts (GAMBL reanalysis)

|Entity|source        |frequency (%)|
|:------:|:--------------:|:-------------:|
|DLBCL |GAMBL genomes |3.44         |
|DLBCL |Schmitz cohort|5.11         |
|DLBCL |Reddy cohort  |2.20         |
|DLBCL |Chapuy cohort |2.56         |

## Mutation pattern and selective pressure estimates

[[include:dnds_UNC5C.md]]



[[include:browser_UNC5C.md]]

## Expression
![](images/gene_expression/UNC5C_by_pathology.svg)
<!-- ORIGIN: Unknown -->

[[include:mermaid_UNC5C.md]]

## References