ZFP36L1
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ZFP36L1 is one of a number of genes affected by aberrant somatic hypermutation in B-cell lymphomas, which complicates the interpretation of mutations at this locus.
| Entity | Tier | Description |
|---|---|---|
 |
2 | relevance in MCL not firmly established |
 |
1 | high-confidence PMBL/cHL/GZL gene[@reichelFlowSortingExome2015] |
 |
2 | aSHM target; Although recurrent, the relevance of mutations in BL is tenuous [@paneaWholeGenomeLandscape2019] |
 |
1 | aSHM target and high-confidence DLBCL gene [@morinFrequentMutationHistonemodifying2011] |
include:DLBCL_ZFP36L1.md include:BL_ZFP36L1.md
| chr_name | hg19_start | hg19_end | region | regulatory_comment |
|---|---|---|---|---|
| chr14 | 69257848 | 69259739 | TSS | active_promoter |
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