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vcf2maf generates an empty maf file #353

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Olsennnnn opened this issue Apr 13, 2024 · 1 comment
Open

vcf2maf generates an empty maf file #353

Olsennnnn opened this issue Apr 13, 2024 · 1 comment

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@Olsennnnn
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Hi,
While running perl vcf2maf.pl --input-vcf newtest.vcf --output-maf test.vep.maf --vep-path /home/data/my/miniconda3/envs/vep/bin/ --vep-data /home/data/my/homo_sapiens/93_GRCh38/ --ref-fasta /home/data/my/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz --ncbi-build GRCh38 --vep-forks 1,
I got a lot of warnings, likeWARNING: Couldn't retrieve bps around 26:16393 from reference FASTA: /home/data/my/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz.
And there is no data in the generated maf file, only the table header, for example Hugo_Symbol,Entrez_Gene_Id,Center, etc
Do you have any suggestion how to solve it?
Thanks
Olsen

@famosab
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famosab commented Nov 19, 2024

Which caller did you use to create the VCF file?

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