diff --git a/CHANGELOG.md b/CHANGELOG.md
index c9f6d96..12f406a 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,11 +10,13 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 ### Added
 
 - Initial release of `tna-python-dev` Docker image
+- Added `uvicorn` support for async applications such as FastAPI
 
 ### Changed
 
 - Update Poetry to [1.7.1](https://github.com/python-poetry/poetry/releases/tag/1.7.1)
 - Updated Base Docker image from `python:3.11-slim` to `python:3.12-slim-bookworm`
+- Install `libcurl4` version `7.88.1-10+deb12u4`
 
 ### Deprecated
 ### Removed
diff --git a/docker/tna-python/Dockerfile b/docker/tna-python/Dockerfile
index 6cdbe6c..e52b5b0 100644
--- a/docker/tna-python/Dockerfile
+++ b/docker/tna-python/Dockerfile
@@ -108,7 +108,7 @@ RUN set -eux; \
     \
     apt-get update; \
     apt-get -y upgrade; \
-    apt-get install -y --no-install-recommends curl=7.88.1-10+deb12u4 build-essential=12.9 libmagic-dev=1:5.44-3; \
+    apt-get install -y --no-install-recommends libcurl4=7.88.1-10+deb12u4 curl=7.88.1-10+deb12u4 build-essential=12.9 libmagic-dev=1:5.44-3; \
     \
     apt-get clean; \
     apt-get autoremove -y --purge; \
diff --git a/docker/tna-python/README.md b/docker/tna-python/README.md
index f3f710e..3637a75 100644
--- a/docker/tna-python/README.md
+++ b/docker/tna-python/README.md
@@ -5,7 +5,8 @@ This image comes with:
 - A version of Python approved by TNA
 - [Poetry](https://python-poetry.org/) for dependency management
 - [nvm](https://github.com/nvm-sh/nvm) for compiling assets such as CSS and JavaScript
-- [Gunicorn](https://gunicorn.org/) for serving the Python application
+- [Gunicorn](https://gunicorn.org/) for serving the Python application via a WSGI
+- [Uvicorn](https://www.uvicorn.org/) for serving the Python application via a ASGI
 
 This image requires you have the following files in the root of your project:
 
@@ -35,12 +36,16 @@ This image requires you have the following files in the root of your project:
 [^6]: [Gunicorn docs - timeout](https://docs.gunicorn.org/en/stable/settings.html#timeout)
 [^7]: [Gunicorn docs - keepalive](https://docs.gunicorn.org/en/stable/settings.html#keepalive)
 
+### Secret key
+
 A secret key (for `SECRET_KEY`) can be generated using:
 
 ```sh
 python -c 'import secrets; print(secrets.token_hex())'
 ```
 
+Alternatively, using the [`tna-dev` image](https://github.com/nationalarchives/docker/tree/main/docker/tna-python-dev), you can run `secret-key` to generate one.
+
 ## Commands for the Dockerfile
 
 There are two commands to use within your `Dockerfile`:
@@ -76,10 +81,22 @@ tna-run my_app:app
 1. Count the number of CPU cores, multiply it by 2 and add 1 to get a suggested worker and thread count
 1. Start `gunicorn` with values appropriate to the environment taking into account any overrides
 
+#### Asynchronous support
+
+For frameworks that require or can use an ASGI rather than a WSGI you can use `tna-run` with a `-a` flag:
+
+```sh
+tna-run -a my_app:app
+```
+
+When working in a development environment (`ENVIRONMENT=production`) and using FastAPI, Uvicorn is used as the ASGI for `tna-run`.
+
+When using FastAPI in production, `tna-run -a` should be explicitly specified so Gunicron can use the Uvicorn worker class.
+
 ## Using Node
 
 To use Node to build your assets you need three files in your project:
 
 - `package.json`
 - `package-lock.json`
-- `.nvmrc`
+- `.nvmrc` containing the version of Node you would like to support (e.g. `lts/iron`)
diff --git a/docker/tna-python/bin/tna-build b/docker/tna-python/bin/tna-build
index 971fbc3..a6c4411 100755
--- a/docker/tna-python/bin/tna-build
+++ b/docker/tna-python/bin/tna-build
@@ -20,4 +20,5 @@ then
 fi
 
 poetry add gunicorn@21.2.0
+poetry add uvicorn@0.25.0
 poetry install --sync --no-root
diff --git a/docker/tna-python/bin/tna-run b/docker/tna-python/bin/tna-run
index 8bb88b5..7cfb331 100755
--- a/docker/tna-python/bin/tna-run
+++ b/docker/tna-python/bin/tna-run
@@ -2,7 +2,28 @@
 
 set -e
 
-if [ -z "$1" ]
+# Set flag defaults
+ASYNC=false
+
+# Parse flags
+while getopts ":a" option; do
+  case "${option}" in
+    a)
+      ASYNC=true
+      shift 1
+      ;;
+    ?)
+      echo "Invalid option: -${OPTARG}"
+      exit 1
+      ;;
+  esac
+done
+
+# Get the application
+APPLICATION=$1
+
+# Error if no application is passed
+if [ -z "$APPLICATION" ]
 then
   echo -e "Error: application not specified in tna-run\n";
   echo "PARAMETERS"
@@ -11,32 +32,50 @@ then
   exit 1
 fi
 
+# Error if $SECRET_KEY is not defined
 if [[ -z $SECRET_KEY ]]
 then
   echo -e "Error: Environment variable SECRET_KEY not set";
   exit 1
 fi
 
+# Convert $ENVIRONMENT to lowercase
+ENVIRONMENT=$(echo "$ENVIRONMENT" | tr '[:upper:]' '[:lower:]')
+
+# If there is an $NPM_DEVELOP_COMMAND and we are running a development environment, run the development command now
 if [ "$ENVIRONMENT" == 'develop' ] && [ -n "$NPM_DEVELOP_COMMAND" ]
 then
   tna-node "$NPM_DEVELOP_COMMAND"
 fi
 
-MAX_REQUESTS=$(python -c "import multiprocessing; print(multiprocessing.cpu_count() * 2 + 1)")
-DEFAULT_WORKERS=$MAX_REQUESTS
-DEFAULT_THREADS=1
+# Set up the default number of workers and threads
+DEFAULT_WORKERS=$(python -c "import multiprocessing; print(multiprocessing.cpu_count() * 2 + 1)")
+DEFAULT_THREADS=$((DEFAULT_WORKERS * 2))
+
+# Set the worker class
+[[ "$ASYNC" = true ]] && WORKER_CLASS=uvicorn.workers.UvicornWorker || WORKER_CLASS=sync
+
+# Use the number of workers and threads (if provided) else use defaults
+[[ -z $WORKERS ]] && WORKERS=$DEFAULT_WORKERS
 [[ -z $THREADS ]] && THREADS=$DEFAULT_THREADS
 
 if [ "$ENVIRONMENT" == 'production' ]
 then
+  # Production environment
   [[ -z $LOG_LEVEL ]] && LOG_LEVEL=warn
-  [[ -z $WORKERS ]] && WORKERS=$DEFAULT_WORKERS
   [[ -z $TIMEOUT ]] && TIMEOUT=30
   [[ -z $KEEP_ALIVE ]] && KEEP_ALIVE=30
-  poetry run gunicorn "$1" --workers "$WORKERS" --threads "$THREADS" --log-level "$LOG_LEVEL" --timeout "$TIMEOUT" --keep-alive "$KEEP_ALIVE" --access-logfile - --bind 0.0.0.0:8080
 elif [ "$ENVIRONMENT" == 'develop' ]
 then
+  # Development environment
   echo "ENVIRONMENT is develop"
+  [[ -z $LOG_LEVEL ]] && LOG_LEVEL=debug
+  [[ -z $WORKERS ]] && WORKERS=3
+  [[ -z $THREADS ]] && THREADS=1
+  [[ -z $TIMEOUT ]] && TIMEOUT=600
+  [[ -z $KEEP_ALIVE ]] && KEEP_ALIVE=5
+
+  # Try using the Django development server if the application uses Django
   echo "Trying Django development server..."
   if poetry show django ;
   then
@@ -44,6 +83,8 @@ then
     poetry run python /app/manage.py runserver 0.0.0.0:8080
   fi
   echo "Django not found"
+
+  # Try using the Flask development server if the application uses Flask
   echo "Trying Flask development server..."
   if poetry show flask ;
   then
@@ -51,16 +92,26 @@ then
     poetry run flask run --debug --host 0.0.0.0 --port 8080
   fi
   echo "Flask not found"
+
+  # Use a uvicorn server if the application uses FastAPI
+  echo "Trying FastAPI server..."
+  if poetry show fastapi ;
+  then
+    echo "FastAPI found, starting server"
+    poetry run uvicorn "$APPLICATION" --workers "$WORKERS" --log-level "$LOG_LEVEL" --timeout-keep-alive "$KEEP_ALIVE" --host 0.0.0.0 --port 8080 --reload
+  fi
+  echo "FastAPI not found"
+
+  # Fall back to using Gunicorn
   echo "No framework found, using Gunicorn to serve development application"
-  [[ -z $LOG_LEVEL ]] && LOG_LEVEL=debug
-  [[ -z $WORKERS ]] && WORKERS=3
-  [[ -z $TIMEOUT ]] && TIMEOUT=600
-  [[ -z $KEEP_ALIVE ]] && KEEP_ALIVE=5
-  poetry run gunicorn "$1" --workers "$WORKERS" --threads "$THREADS" --log-level "$LOG_LEVEL" --timeout "$TIMEOUT" --keep-alive "$KEEP_ALIVE" --reload --bind 0.0.0.0:8080
+  poetry run gunicorn "$APPLICATION" --workers "$WORKERS" --threads "$THREADS" --log-level "$LOG_LEVEL" --timeout "$TIMEOUT" --keep-alive "$KEEP_ALIVE" --bind 0.0.0.0:8080 --worker-class="$WORKER_CLASS" --reload
 else
+  # All other environments
   [[ -z $LOG_LEVEL ]] && LOG_LEVEL=info
-  [[ -z $WORKERS ]] && WORKERS=$DEFAULT_WORKERS
   [[ -z $TIMEOUT ]] && TIMEOUT=30
   [[ -z $KEEP_ALIVE ]] && KEEP_ALIVE=5
-  poetry run gunicorn "$1" --workers "$WORKERS" --threads "$THREADS" --log-level "$LOG_LEVEL" --timeout "$TIMEOUT" --keep-alive "$KEEP_ALIVE" --access-logfile - --bind 0.0.0.0:8080
 fi
+
+# Start the server
+echo "Starting $ENVIRONMENT server"
+poetry run gunicorn "$APPLICATION" --workers "$WORKERS" --threads "$THREADS" --log-level "$LOG_LEVEL" --timeout "$TIMEOUT" --keep-alive "$KEEP_ALIVE" --access-logfile - --bind 0.0.0.0:8080 --worker-class="$WORKER_CLASS"