diff --git a/ci/azure-wheel-test-upload.yml b/ci/azure-wheel-test-upload.yml
index 7092734b1b..702961ffe3 100644
--- a/ci/azure-wheel-test-upload.yml
+++ b/ci/azure-wheel-test-upload.yml
@@ -9,7 +9,7 @@ steps:
       brew install python
       export SKIP_EMBEDED_PYTHON_TEST=true
       packaging/python/test_wheels.sh /usr/local/bin/python3 wheelhouse/*.whl
-    condition: and(eq(variables['agent.os'], 'Darwin'), eq(variables['python.version'], '3.7'))
+    condition: and(eq(variables['agent.os'], 'Darwin'), eq(variables['python.version'], '3.9'))
     displayName: 'Test with brew Python'
 
   - task: UsePythonVersion@0
diff --git a/ci/azure-win-installer-upload.yml b/ci/azure-win-installer-upload.yml
index c75bd701a3..f07739c7bd 100644
--- a/ci/azure-win-installer-upload.yml
+++ b/ci/azure-win-installer-upload.yml
@@ -7,7 +7,7 @@ steps:
 
   - task: UsePythonVersion@0
     inputs:
-      versionSpec: '3.7'
+      versionSpec: '3.9'
     displayName: "Use System Python"
 
   - task: BatchScript@1
diff --git a/ci/win_build_cmake.sh b/ci/win_build_cmake.sh
index 940246cda2..0aa3377a0c 100755
--- a/ci/win_build_cmake.sh
+++ b/ci/win_build_cmake.sh
@@ -30,9 +30,9 @@ cd $BUILD_SOURCESDIRECTORY/build
 	-DNRN_ENABLE_PYTHON=ON  \
 	-DNRN_ENABLE_RX3D=ON  \
 	-DNRN_RX3D_OPT_LEVEL=2 \
-	-DPYTHON_EXECUTABLE=/c/Python37/python.exe \
+	-DPYTHON_EXECUTABLE=/c/Python39/python.exe \
 	-DNRN_ENABLE_PYTHON_DYNAMIC=ON  \
-	-DNRN_PYTHON_DYNAMIC='c:/Python37/python.exe;c:/Python38/python.exe;c:/Python39/python.exe;c:/Python310/python.exe;c:/Python311/python.exe;c:/Python312/python.exe;c:/Python313/python.exe'  \
+	-DNRN_PYTHON_DYNAMIC='c:/Python39/python.exe;c:/Python310/python.exe;c:/Python311/python.exe;c:/Python312/python.exe;c:/Python313/python.exe'  \
 	-DCMAKE_INSTALL_PREFIX='/c/nrn-install' \
 	-DMPI_CXX_LIB_NAMES:STRING=msmpi \
 	-DMPI_C_LIB_NAMES:STRING=msmpi \
diff --git a/ci/win_download_deps.cmd b/ci/win_download_deps.cmd
index 9c9e8d8ad3..c66a0b510f 100644
--- a/ci/win_download_deps.cmd
+++ b/ci/win_download_deps.cmd
@@ -3,8 +3,6 @@
 :: download all installers
 
 :: python
-pwsh -command Invoke-WebRequest -MaximumRetryCount 4 -OutFile python-3.7.exe https://www.python.org/ftp/python/3.7.7/python-3.7.7-amd64.exe || goto :error
-pwsh -command Invoke-WebRequest -MaximumRetryCount 4 -OutFile python-3.8.exe https://www.python.org/ftp/python/3.8.2/python-3.8.2-amd64.exe || goto :error
 pwsh -command Invoke-WebRequest -MaximumRetryCount 4 -OutFile python-3.9.exe https://www.python.org/ftp/python/3.9.0/python-3.9.0-amd64.exe || goto :error
 pwsh -command Invoke-WebRequest -MaximumRetryCount 4 -OutFile python-3.10.exe https://www.python.org/ftp/python/3.10.0/python-3.10.0-amd64.exe || goto :error
 pwsh -command Invoke-WebRequest -MaximumRetryCount 4 -OutFile python-3.11.exe https://www.python.org/ftp/python/3.11.1/python-3.11.1-amd64.exe || goto :error
diff --git a/ci/win_install_deps.cmd b/ci/win_install_deps.cmd
index ac12eb5bcd..cea4da4fe2 100644
--- a/ci/win_install_deps.cmd
+++ b/ci/win_install_deps.cmd
@@ -3,8 +3,6 @@
 :: install all dependencies
 
 :: install python
-python-3.7.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustForMeTargetDir=C:\Python37 || goto :error
-python-3.8.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustForMeTargetDir=C:\Python38 || goto :error
 python-3.9.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustForMeTargetDir=C:\Python39 || goto :error
 python-3.10.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustForMeTargetDir=C:\Python310 || goto :error
 python-3.11.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustForMeTargetDir=C:\Python311 || goto :error
@@ -12,23 +10,17 @@ python-3.12.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustF
 python-3.13.exe /passive Include_pip=1 Include_test=0 PrependPath=1 DefaultJustForMeTargetDir=C:\Python313 || goto :error
 
 :: fix msvcc version for all python3
-pwsh -command "(Get-Content C:\Python37\Lib\distutils\cygwinccompiler.py) -replace 'elif msc_ver == ''1600'':', 'elif msc_ver == ''1900'':' | Out-File C:\Python37\Lib\distutils\cygwinccompiler.py"
-pwsh -command "(Get-Content C:\Python38\Lib\distutils\cygwinccompiler.py) -replace 'elif msc_ver == ''1600'':', 'elif msc_ver == ''1916'':' | Out-File C:\Python38\Lib\distutils\cygwinccompiler.py"
 pwsh -command "(Get-Content C:\Python39\Lib\distutils\cygwinccompiler.py) -replace 'elif msc_ver == ''1600'':', 'elif msc_ver == ''1927'':' | Out-File C:\Python39\Lib\distutils\cygwinccompiler.py"
 pwsh -command "(Get-Content C:\Python310\Lib\distutils\cygwinccompiler.py) -replace 'elif msc_ver == ''1600'':', 'elif msc_ver == ''1929'':' | Out-File C:\Python310\Lib\distutils\cygwinccompiler.py"
 pwsh -command "(Get-Content C:\Python311\Lib\distutils\cygwinccompiler.py) -replace 'elif msc_ver == ''1600'':', 'elif msc_ver == ''1934'':' | Out-File C:\Python311\Lib\distutils\cygwinccompiler.py"
 
 
 :: fix msvc runtime library for all python
-pwsh -command "(Get-Content C:\Python37\Lib\distutils\cygwinccompiler.py) -replace 'msvcr100', 'msvcrt' | Out-File C:\Python37\Lib\distutils\cygwinccompiler.py"
-pwsh -command "(Get-Content C:\Python38\Lib\distutils\cygwinccompiler.py) -replace 'msvcr100', 'msvcrt' | Out-File C:\Python38\Lib\distutils\cygwinccompiler.py"
 pwsh -command "(Get-Content C:\Python39\Lib\distutils\cygwinccompiler.py) -replace 'msvcr100', 'msvcrt' | Out-File C:\Python39\Lib\distutils\cygwinccompiler.py"
 pwsh -command "(Get-Content C:\Python310\Lib\distutils\cygwinccompiler.py) -replace 'msvcr100', 'msvcrt' | Out-File C:\Python310\Lib\distutils\cygwinccompiler.py"
 pwsh -command "(Get-Content C:\Python311\Lib\distutils\cygwinccompiler.py) -replace 'msvcr100', 'msvcrt' | Out-File C:\Python311\Lib\distutils\cygwinccompiler.py"
 
 :: install numpy
-C:\Python37\python.exe -m pip install numpy==1.14.6 cython || goto :error
-C:\Python38\python.exe -m pip install  numpy==1.17.5 cython || goto :error
 C:\Python39\python.exe -m pip install  numpy==1.19.3 cython || goto :error
 C:\Python310\python.exe -m pip install numpy==1.21.3 cython || goto :error
 C:\Python311\python.exe -m pip install numpy==1.23.5 cython || goto :error
diff --git a/ci/win_test_installer.cmd b/ci/win_test_installer.cmd
index df6c44f67a..9c8f11e210 100644
--- a/ci/win_test_installer.cmd
+++ b/ci/win_test_installer.cmd
@@ -17,8 +17,6 @@ echo %NEURONHOME%
 if not exist association.hoc.out (start /wait /REALTIME %cd%\ci\association.hoc)
 
 :: test all pythons
-C:\Python37\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
-C:\Python38\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python39\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python310\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python311\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
@@ -26,8 +24,6 @@ C:\Python312\python -c "import neuron; neuron.test(); quit()" || set "errorfound
 C:\Python313\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 
 :: install oldest supported numpy
-C:\Python37\python.exe -m pip install -r packaging/python/oldest_numpy_requirements.txt || goto :error
-C:\Python38\python.exe -m pip install -r packaging/python/oldest_numpy_requirements.txt || goto :error
 C:\Python39\python.exe -m pip install -r packaging/python/oldest_numpy_requirements.txt || goto :error
 C:\Python310\python.exe -m pip install -r packaging/python/oldest_numpy_requirements.txt || goto :error
 C:\Python311\python.exe -m pip install -r packaging/python/oldest_numpy_requirements.txt || goto :error
@@ -35,8 +31,6 @@ C:\Python312\python.exe -m pip install -r packaging/python/oldest_numpy_requirem
 C:\Python313\python.exe -m pip install -r packaging/python/oldest_numpy_requirements.txt || goto :error
 
 :: test all pythons again
-C:\Python37\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
-C:\Python38\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python39\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python310\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python311\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
diff --git a/ci/win_test_installer_wo_rxd.cmd b/ci/win_test_installer_wo_rxd.cmd
index 86e49d0e40..d33c40c0d4 100644
--- a/ci/win_test_installer_wo_rxd.cmd
+++ b/ci/win_test_installer_wo_rxd.cmd
@@ -20,8 +20,6 @@ echo %NEURONHOME%
 if not exist association.hoc.out (start /wait /REALTIME %cd%\ci\association.hoc)
 
 :: test all pythons
-C:\Python37\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
-C:\Python38\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python39\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python310\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"
 C:\Python311\python -c "import neuron; neuron.test(); quit()" || set "errorfound=y"