diff --git a/recipes/pysam/build.sh b/recipes/pysam/build.sh
index 7149da7474346..ebbeba552cab5 100644
--- a/recipes/pysam/build.sh
+++ b/recipes/pysam/build.sh
@@ -6,7 +6,7 @@ sed -i'' -e 's/"-Wno-error=declaration-after-statement"//g' setup.py
 # linking htslib, see:
 # http://pysam.readthedocs.org/en/latest/installation.html#external
 # https://github.com/pysam-developers/pysam/blob/v0.9.0/setup.py#L79
-#export HTSLIB_LIBRARY_DIR=$PREFIX/lib:$HTSLIB_LIBRARY_DIR
-#export HTSLIB_INCLUDE_DIR=$PREFIX/include:$HTSLIB_INCLUDE_DIR
+#export HTSLIB_LIBRARY_DIR=$PREFIX/lib
+#export HTSLIB_INCLUDE_DIR=$PREFIX/include
 sed -i'' -e 's/HTSLIB_MODE = \"shared\"/HTSLIB_MODE = \"separate\"/g' setup.py
 $PYTHON setup.py install
diff --git a/recipes/pysam/meta.yaml b/recipes/pysam/meta.yaml
index 8ed6038c034ad..9fbb453b62a66 100644
--- a/recipes/pysam/meta.yaml
+++ b/recipes/pysam/meta.yaml
@@ -8,10 +8,12 @@ source:
     md5: 66913000ff50817bdcf56dfd3a52396f
 
 build:
-    number: 0
+    number: 1
 
 requirements:
     build:
+        - gcc  # [linux]
+        - llvm # [osx]
         - htslib
         - samtools
         - bcftools
@@ -20,6 +22,7 @@ requirements:
         - setuptools
 
     run:
+        - libgcc # [linux]
         - htslib
         - samtools
         - bcftools