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library(nlmixr2) #> Loading required package: nlmixr2data library(tidyverse) set.seed(42) rxode2::rxSetSeed(42) iv1cmt <- function() { ini({ tV <- 1 tCL <- 0.2 prop.err <- 0.1 }) model({ V <- tV CL <- tCL d/dt(X) = -(CL/V)*X cp = X/V cp ~ prop(prop.err) }) } e <- et(amt=1000, rate=500) %>% et(0.1, 24, length.out=24) dat <- rxode2::rxSolve(iv1cmt, e, addDosing = TRUE) dat <- dat %>% mutate(ID=1, DV=ifelse(is.na(amt), sim, NA)) %>% select(ID, evid, cmt, amt, rate, time, DV) f <- nlmixr(iv1cmt) fit <- nlmixr(f, dat, est="focei", control=list(print=0, outerOpt="bobyqa")) #> rxode2 2.0.12 using 8 threads (see ?getRxThreads) #> no cache: create with `rxCreateCache()` #> calculating covariance matrix #> done #> → Calculating residuals/tables #> ✔ done #> → compress origData in nlmixr2 object, save 2136 #> → compress parHist in nlmixr2 object, save 3088 plot(fit)
Created on 2023-03-23 with reprex v2.0.2
The text was updated successfully, but these errors were encountered:
Missing:
They used to be there this is some sort of regression I believe.
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Created on 2023-03-23 with reprex v2.0.2
The text was updated successfully, but these errors were encountered: