diff --git a/tests/drivers/uart/uart_async_api/boards/nrf5340bsim_nrf5340_cpuapp.conf b/tests/drivers/uart/uart_async_api/boards/nrf5340bsim_nrf5340_cpuapp.conf
new file mode 100644
index 00000000000..e7a460fde6b
--- /dev/null
+++ b/tests/drivers/uart/uart_async_api/boards/nrf5340bsim_nrf5340_cpuapp.conf
@@ -0,0 +1,2 @@
+CONFIG_UART_1_NRF_HW_ASYNC_TIMER=1
+CONFIG_UART_NRFX_UARTE_ENHANCED_RX=y
diff --git a/tests/drivers/uart/uart_async_api/boards/nrf5340bsim_nrf5340_cpuapp.overlay b/tests/drivers/uart/uart_async_api/boards/nrf5340bsim_nrf5340_cpuapp.overlay
new file mode 100644
index 00000000000..bfd4f8676f1
--- /dev/null
+++ b/tests/drivers/uart/uart_async_api/boards/nrf5340bsim_nrf5340_cpuapp.overlay
@@ -0,0 +1,3 @@
+/* SPDX-License-Identifier: Apache-2.0 */
+
+#include "nrf5340dk_nrf5340_cpuapp.overlay"
diff --git a/tests/drivers/uart/uart_async_api/testcase.yaml b/tests/drivers/uart/uart_async_api/testcase.yaml
index e7a970d4a58..1433691d2a7 100644
--- a/tests/drivers/uart/uart_async_api/testcase.yaml
+++ b/tests/drivers/uart/uart_async_api/testcase.yaml
@@ -26,7 +26,10 @@ tests:
     integration_platforms:
       - nucleo_h743zi
   drivers.uart.async_api.nrf_uarte_new:
-    platform_allow: nrf52840dk/nrf52840 nrf52_bsim
+    platform_allow:
+      - nrf52840dk/nrf52840
+      - nrf52_bsim
+      - nrf5340bsim/nrf5340/cpuapp
     filter: CONFIG_SERIAL_SUPPORT_ASYNC
     harness: ztest
     harness_config: