diff --git a/src/openforms/tests/e2e/data/test.msg b/src/openforms/tests/e2e/data/test.msg
new file mode 100644
index 0000000000..b597796de6
Binary files /dev/null and b/src/openforms/tests/e2e/data/test.msg differ
diff --git a/src/openforms/tests/e2e/test_file_upload.py b/src/openforms/tests/e2e/test_file_upload.py
index f0001aa773..bd6be71435 100644
--- a/src/openforms/tests/e2e/test_file_upload.py
+++ b/src/openforms/tests/e2e/test_file_upload.py
@@ -77,3 +77,64 @@ def setUpTestData():
                 await expect(
                     page.get_by_text("Een moment geduld", exact=False)
                 ).to_be_visible()
+
+    async def test_form_with_msg_file_upload(self):
+        # If using the ci.py settings locally, the SDK_RELEASE  variable should be set to 'latest', otherwise the
+        # JS/CSS for the SDK will not be found (since they will be expected to be in the folder
+        # openforms/static/sdk/<SDK version tag> instead of openforms/static/sdk
+        @sync_to_async
+        def setUpTestData():
+            # set up a form
+            form = FormFactory.create(
+                name="Form with file upload",
+                slug="form-with-file-upload",
+                generate_minimal_setup=True,
+                formstep__form_definition__name="First step",
+                formstep__form_definition__slug="first-step",
+                formstep__form_definition__configuration={
+                    "components": [
+                        {
+                            "type": "file",
+                            "key": "fileUpload",
+                            "label": "File Upload",
+                            "storage": "url",
+                            "validate": {
+                                "required": True,
+                            },
+                        }
+                    ]
+                },
+                translation_enabled=False,  # force Dutch
+                ask_privacy_consent=False,
+                ask_statement_of_truth=False,
+            )
+            return form
+
+        form = await setUpTestData()
+        form_url = str(
+            furl(self.live_server_url)
+            / reverse("forms:form-detail", kwargs={"slug": form.slug})
+        )
+
+        with patch("openforms.utils.validators.allow_redirect_url", return_value=True):
+            async with browser_page() as page:
+                await page.goto(form_url)
+
+                await page.get_by_role("button", name="Formulier starten").click()
+
+                async with page.expect_file_chooser() as fc_info:
+                    await page.get_by_text("blader").click()
+
+                file_chooser = await fc_info.value
+                await file_chooser.set_files(TEST_FILES / "test.msg")
+
+                await page.wait_for_load_state("networkidle")
+
+                uploaded_file = page.get_by_role("link", name="test.msg")
+                await expect(uploaded_file).to_be_visible()
+
+                await page.get_by_role("button", name="Volgende").click()
+                await page.get_by_role("button", name="Verzenden").click()
+                await expect(
+                    page.get_by_text("Een moment geduld", exact=False)
+                ).to_be_visible()