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reading bigwigs into dataframes #153

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gfudenberg opened this issue May 25, 2023 · 0 comments
Open

reading bigwigs into dataframes #153

gfudenberg opened this issue May 25, 2023 · 0 comments
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@gfudenberg
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summarizing nvictus/pybbi#25:

proposal to add two functions to https://github.com/open2c/bioframe/tree/main/bioframe/sandbox, perhaps in a new bigwig_extras.py:

  • generate a matrix of [n_intervals x nbins] with binned ChIP signal across each of the intervals in an interval_df (then often visualized as a heatmap)
  • generate a vector of [n_intervals x 1 bins] of total ChIP signal across each interval and return a column (also have a kwarg append=False)
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@gfudenberg