diff --git a/meson.build b/meson.build
new file mode 100644
index 000000000..2a98039ef
--- /dev/null
+++ b/meson.build
@@ -0,0 +1,24 @@
+project('euphonic', 'c', meson_version: '>=1.1')
+
+build = get_option('python_only') ? disabler() : []
+
+src = ['c/_euphonic.c', 'c/dyn_mat.c', 'c/util.c', 'c/py_util.c', 'c/load_libs.c']
+
+openmp = dependency('openmp', required: false, language: 'c')
+
+py = import('python').find_installation(pure: false)
+py_dep = py.dependency()
+
+np = dependency('numpy', required: false)
+
+if not np.found() # Try default
+  np_inc = include_directories(py.get_path('platlib') / 'numpy/core/include')
+  np = declare_dependency(include_directories: np_inc)
+endif
+
+py.extension_module(
+  '_euphonic',
+  src,
+  dependencies: [build, py_dep, np, openmp],
+  install: true,
+)
diff --git a/meson.options b/meson.options
new file mode 100644
index 000000000..75a53ee1b
--- /dev/null
+++ b/meson.options
@@ -0,0 +1 @@
+option('python_only', type : 'boolean', value : false)
diff --git a/pyproject.toml b/pyproject.toml
index 85107557a..d67c6c7e4 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -1,3 +1,10 @@
+[build-system]
+build-backend = 'mesonpy'
+requires = ["meson-python",
+            "packaging",
+            "numpy>=1.24.0",
+            "versioneer[toml]==0.29"]
+
 [project]
 name = "Euphonic"
 description = "Euphonic calculates phonon bandstructures and inelastic neutron scattering intensities from modelling code output (e.g. CASTEP)"
@@ -33,13 +40,6 @@ dependencies = [
 ]
 dynamic = ["version"]
 
-[build-system]
-requires = ["packaging",
-            "numpy>=1.24.0",
-            "versioneer[toml]==0.29",
-            "setuptools>=61.0.0"]
-build-backend = "setuptools.build_meta"
-
 [project.urls]
 Homepage = "https://github.com/pace-neutrons/Euphonic"
 Repository = "https://github.com/pace-neutrons/Euphonic.git"
@@ -67,6 +67,3 @@ versionfile_source = "euphonic/_version.py"
 versionfile_build = "euphonic/_version.py"
 tag_prefix = "v"
 parentdir_prefix = "Euphonic-"
-
-[tool.setuptools.packages.find]
-include = ["euphonic*"]
\ No newline at end of file