-
Notifications
You must be signed in to change notification settings - Fork 5
/
conso.owl
14418 lines (12642 loc) · 947 KB
/
conso.owl
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
<?xml version="1.0"?>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xml:base="https://raw.githubusercontent.com/pharmacome/conso/master/export/conso.owl"
xmlns="https://raw.githubusercontent.com/pharmacome/conso/master/export/conso.owl#"
xmlns:skos="http://www.w3.org/2008/05/skos#">
<owl:Ontology rdf:about="https://raw.githubusercontent.com/pharmacome/conso/master/export/conso.owl"/>
<owl:AnnotationProperty rdf:about="http://www.w3.org/2008/05/skos#altLabel"/>
<owl:AnnotationProperty rdf:about="http://www.w3.org/2008/05/skos#related"/>
<owl:AnnotationProperty rdf:about="#author"/>
<owl:AnnotationProperty rdf:about="#bel"/>
<owl:Class rdf:about="#CONSOC0">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">?</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC1">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">anatomy</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC2">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">antibody</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC3">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">aptamer</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC4">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">biological process</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC5">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cellular component</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC6">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chemical</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC7">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chemical (proprietary)</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC8">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chemical class</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC9">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chemical mixture</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC10">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chemical role</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC11">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">clinical measurement</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC12">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">domain</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC13">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">enzyme class</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC14">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">epitope</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC15">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">exposure</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC16">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">genetic variant</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC17">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">isoform</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC18">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">molecular function</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC19">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">motif</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC20">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pathology</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC21">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pathway</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC22">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">peptide</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC23">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">post-translational modification</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC24">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC25">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein complex</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC26">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein family</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC27">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein fragment</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC28">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein isoform family</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSOC29">
<rdfs:subClassOf rdf:resource="http://www.w3.org/2002/07/owl#Thing"/>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">protein variant</rdfs:label>
</owl:Class>
<owl:Class rdf:about="#CONSO00001">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">The motif in the MAPT protein where microtubule binding repeats</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-binding region</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MTBR</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18500754</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:2516729</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">interpro:IPR001084</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00002">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">position 569_591 of canonical isoform of MAPT protein</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">tubulin-binding repeat 1</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MTBR R1</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">R1</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18500754</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
<bel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">p(HGNC:MAPT, frag(569_591))</bel>
</owl:Class>
<owl:Class rdf:about="#CONSO00003">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">position 592_621 of canonical isoform of MAPT protein</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">tubulin-binding repeat 2</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MTBR R2</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">R2</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18500754</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
<bel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">p(HGNC:MAPT, frag(592_621))</bel>
</owl:Class>
<owl:Class rdf:about="#CONSO00004">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">position 623_653 of canonical isoform of MAPT protein</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">tubulin-binding repeat 3</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MTBR R3</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">R3</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18500754</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
<bel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">p(HGNC:MAPT, frag(623_653))</bel>
</owl:Class>
<owl:Class rdf:about="#CONSO00005">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">position 654_685 of canonical isoform of MAPT protein</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">tubulin-binding repeat 4</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MTBR R4</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">R4</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18500754</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
<bel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">p(HGNC:MAPT, frag(654_685))</bel>
</owl:Class>
<owl:Class rdf:about="#CONSO00006">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau (MAPT) in its aggregated form (as Paired Helical Filaments (PHFs) or Straight Filaments (SF)) contains 5–9 moles of phosphate/ mole of the protein, defining it as hyper phosphorylated</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau aggregates</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pmc:PMC2633703</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00007">
<rdfs:subClassOf rdf:resource="#CONSOC23"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">An excessive phosphorylation (see GO:0006468)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hyperphosphorylation</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:22710920</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00008">
<rdfs:subClassOf rdf:resource="#CONSOC15"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">temperature-sensitive allele of GAL80 (tub-GAL80TS)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GAL80TS</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pmc:PMC3073608</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-6117-4413</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00009">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAST is known to prevent oligomerization of Tau (Rao et al., 2014) and α-synuclein (Diepenbroek et al. 2014) and inhibit reactive gliosis (Rao et al., 2008)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau oligomers</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pmc:PMC4828294</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-6117-4413</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00010">
<rdfs:subClassOf rdf:resource="#CONSOC6"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">a typo appearing in pubmed:23950935 for the specific PI3-kinase inhibitor that is actually named LY294002</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY293002</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">154447-36-6</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">15447-36-6</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1yi3</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-(4-morpholino)-8-phenyl-4H-1-benzopyran-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-(morpholin-4-yl)-8-phenyl-4H-chromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-(morpholin-4-yl)-8-phenylchromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-Morpholin-4-yl-8-phenyl-chromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-Morpholino-8-phenyl-4-oxo-4H-1-benzopyran</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-Morpholino-8-phenylchromone</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-morpholin-4-yl-8-phenyl-4H-chromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-morpholin-4-yl-8-phenylchromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-morpholino-8-phenyl-4H-chromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2-morpholino-8-phenyl-chromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">31M2U1DVID</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4CA-0787</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl- (9CI)</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-(9CI)</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4H-1-Benzopyran-4-one,2-(4-morpholinyl)-8-phenyl-</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4azt</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">8-Phenyl-2-(morpholin-4-yl)-chromen-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AB0033714</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AC-30295</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AC1L1H4N</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AC1Q6CLU</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AK162301</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AKOS017344742</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AN-1305</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">API0015880</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AS-16252</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BC660045</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BCBcMAP01_000117</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BCP00195</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BCP9000880</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BCPP000177</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BDBM12915</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BIL2940</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BMK1-D5</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BRD-K27305650-001-05-9</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BSPBio_001223</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bio1_000332</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bio1_000821</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bio1_001310</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bio2_000442</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Bio2_000922</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BiomolKI2_000037</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BiomolKI_000029</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C15195</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CBiol_002046</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CCG-100633</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:65329</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEMBL98350</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CS-0150</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CTK0H1979</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CZQHHVNHHHRRDU-UHFFFAOYSA-N</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">D09SFV</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">D0X7NA</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DB02656</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DTXSID6042650</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">EC-000.2341</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">EX-A073</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">FT-0660382</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GTPL6004</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl- (9CI)</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">H-1-Benzopyran-4-one, 2-(4-morpholinyl)-8-phenyl-(9CI)</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS1362M05</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS1792M05</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS1990M05</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS3229G17</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS3403M05</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS3649E04</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS3654M21</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HSCI1_000206</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HY-10108</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IDI1_002197</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IN1266</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">IN1268</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">InSolution&trade; LY 294002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">J-510126</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">K00235</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KB-19284</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KB-231805</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBio2_000563</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBio2_003131</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBio2_005699</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBio3_001005</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBio3_001006</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBioGR_000563</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KBioSS_000563</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KS-00000XP3</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Kinome_3543</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LS-39828</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY 294002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY 294002, LY-294002, 154447-36-6</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY 294002; 2-(4-Morpholino)-8-phenyl-4H-1-benzopyran-4-one</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY-294,002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY-294,002 hydrochloride, solid, >=98% (HPLC)</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY-294002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY-924002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY2</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LY294002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Lopac-L-9908</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Lopac0_000710</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Lys 294002</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">M2410</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MLS006010131</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MolPort-003-983-779</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-01</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-02</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-03</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-04</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-05</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-06</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00015622-07</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00025020-01</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00025020-02</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00025020-03</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00025020-04</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00179253-01</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCI60_034712</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NSC 697286</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NSC-697286</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NSC697286</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PubChem16766</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">QC-7260</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RS0074</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RT-013609</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">S-7706</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SB10965</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SC-85850</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SCHEMBL94377</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SF 1101</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SF-1101</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SMR002530642</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SR-01000076245-7</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ST24040926</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SW217688-2</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SYN1108</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tocris-1130</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">UNII-31M2U1DVID</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">X7411</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ZINC6014</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ZX-AFC000490</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cc-58</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">s1105</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23950935</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cas:154447-36-6</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chebi:CHEBI:65329</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">drugbank:DB02656</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">inchi:InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubchem.compound:3973</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">smiles:C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00011">
<rdfs:subClassOf rdf:resource="#CONSOC15"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Low-power laser irradiation (LPLI) is a non-damage physical therapy</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LPLI</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Low-power laser irradiation</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:20333643</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00012">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chronic cerebral hypoperfusion (CCH) is one of the causes of vascular dementia (VaD) and is also an etiological factor for Alzheimer's disease (AD)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Chronic cerebral hypoperfusion</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CCH</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:24575038</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00013">
<rdfs:subClassOf rdf:resource="#CONSOC9"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ethanol extracted from Mori Fructus, a well-known traditional herbal medicine, food, and dietary supplement</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Mori Fructus ethanol extract</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ME</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:26068423</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00014">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">filamentous-actin-containing membranous structures that bridge and connect cells</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">tunneling nanotubes</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">TNT</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">membrane nanotube</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:27809932</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00015">
<rdfs:subClassOf rdf:resource="#CONSOC4"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">production of amyloid</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">amyloidogenesis</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:24653673</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00016">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">alpha-synuclein (SNCA) aggregate in fibrillar or oligomeric forms, usually found in Lewy bodies</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">alpha-synuclein aggregates</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23254192</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00017">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">huntingtin (HTT) protein fragments aggregations</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">huntingtin aggregates</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:12747895</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00018">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">aggregation of amyloid-beta fragments of the APP protein</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">amyloid-beta aggregates</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23484434</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00019">
<rdfs:subClassOf rdf:resource="#CONSOC6"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A tau aggregation inhibitor</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SEN-1269</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-((5-(3-(Dimethylamino)phenoxy)pyrimidin-2-yl)amino)phenol</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-(5-(3-(dimethylamino)phenoxy)pyrimidin-2-ylamino)phenol</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-({5-[3-(dimethylamino)phenoxy]pyrimidin-2-yl}amino)phenol</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-[[5-[3-(dimethylamino)phenoxy]-2-pyrimidinyl]amino]phenol</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4350AF</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">956128-01-1</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A11161</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AKOS015850742</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEMBL2386874</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CTK5H7888</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DB-080315</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DTXSID40676566</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">FT-0682533</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">I06-2365</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MFPAAKZZUIRMKR-UHFFFAOYSA-N</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MolPort-009-685-119</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00387448-01</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SCHEMBL3602388</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SEN 1269</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">TC-064564</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ZINC49582255</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23484434</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chembl:CHEMBL2386874</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">inchi:InChI=1S/C18H18N4O2/c1-22(2)14-6-4-8-16(10-14)24-17-11-19-18(20-12-17)21-13-5-3-7-15(23)9-13/h3-12,23H,1-2H3,(H,19,20,21)</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubchem.compound:46835756</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">smiles:CN(C)C1=CC(=CC=C1)OC2=CN=C(N=C2)NC3=CC(=CC=C3)O</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00020">
<rdfs:subClassOf rdf:resource="#CONSOC6"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A tau aggregation inhibitor</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MLS000034832</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">123542-47-2</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-Phenyl-4-oxo-5-amino-3,4-dihydrothieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">5-Amino-4-oxo-3-phenyl-3,4-dihydro-thieno[3,4-d]pyridazine-1-carboxylic acid eth</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">5-Amino-4-oxo-3-phenyl-3,4-dihydro-thieno[3,4-d]pyridazine-1-carboxylic acid ethyl ester</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AC1LDGR2</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AC1Q34EJ</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AKOS000601368</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BAS 06046551</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">BDBM50253793</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CCG-115473</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEMBL461431</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">F2135-0238</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HLVGVGCIJRBRQW-UHFFFAOYSA-N</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS1616C21</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">HMS2339G13</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">L-4233</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MCULE-6208802152</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MLS000034832</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MLS002539346</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MolPort-001-835-700</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">NCGC00031883-02</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SCHEMBL7885074</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SMR000013604</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ZINC563211</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ethyl 5-amino-4-oxo-3-phenyl-3,4-dihydrothieno[3,4-d]pyridazine-1-carboxylate</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ethyl 5-amino-4-oxo-3-phenyl-3H,4H-thieno[3,4-d]pyridazine-1-carboxylate</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ethyl 5-amino-4-oxo-3-phenylthieno[3,4-d]pyridazine-1-carboxylate</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23484434</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chembl:CHEMBL461431</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">inchi:InChI=1S/C15H13N3O3S/c1-2-21-15(20)12-10-8-22-13(16)11(10)14(19)18(17-12)9-6-4-3-5-7-9/h3-8H,2,16H2,1H3</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubchem.compound:647821</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">smiles:CCOC(=O)C1=NN(C(=O)C2=C(SC=C21)N)C3=CC=CC=C3</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00021">
<rdfs:subClassOf rdf:resource="#CONSOC6"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A tau aggregation inhibitor</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">caprospinol</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">((20S,22R,25R)-Spirosta-5-ene-3beta-ol)hexanoate</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(22R,25R)-20alpha-Spirost-5-en-3beta-yl hexanoate</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(3beta,8xi,9xi,14xi,16xi,17xi,20R,22xi,25R)-Spirost-5-en-3-yl hexanoa</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4952-56-1</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">9BU4T267E4</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AKOS015955746</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAPROSPINOL</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DB05263</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Diosgenin caproate</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Diosgenin, hexanoate</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">J2.343.184J</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MCULE-6852340934</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MolPort-002-507-344</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SP-223</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SP-233</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Spirost-5-en-3-ol, 3-hexanoate, (3beta,25R)-</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">UNII-9BU4T267E4</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ZINC97971833</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23484434</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">drugbank:DB05263</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">inchi:InChI=1S/C33H52O4/c1-6-7-8-9-29(34)36-24-13-15-31(4)23(18-24)10-11-25-26(31)14-16-32(5)27(25)19-28-30(32)22(3)33(37-28)17-12-21(2)20-35-33/h10,21-22,24-28,30H,6-9,11-20H2,1-5H3/t21-,22+,24+,25-,26+,27+,28+,30+,31+,32+,33-/m1/s1</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubchem.compound:16394575</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">smiles:CCCCCC(=O)O[C@H]1CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](C[C@@H]5O[C@]6(CC[C@@H](C)CO6)[C@@H](C)[C@H]45)[C@@H]3CC=C2C1</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00022">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Small aggregates of amyloid-beta</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">amyloid-beta oligomers</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:29196815</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:24918635</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00023">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Amyloid-beta oligomers composed specifically of amyloid-beta 42</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">amyloid-beta 42 oligomers</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:24918635</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00024">
<rdfs:subClassOf rdf:resource="#CONSOC27"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C-terminally truncated carboxyl-terminal fragments (CTFs) of APP</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">APP C-terminally truncated carboxyl-terminal fragments</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:15491160</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00025">
<rdfs:subClassOf rdf:resource="#CONSOC14"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A2B5 antigen is a cell surface ganglioside epitope expressed on developing thymic epithelial cells, oligodendrocyte progenitors, and neuroendocrine cells.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A2B5 antigen</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:1497614</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00026">
<rdfs:subClassOf rdf:resource="#CONSOC13"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Sphingomyelin phosphodiesterase (EC 3.1.4.12, also known as neutral sphingomyelinase, sphingomyelinase, or SMase) is a hydrolase enzyme that is involved in sphingolipid metabolism reactions.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">neutral sphingomyelinase</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:19519303</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ec-code:3.1.4.12</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00027">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Neurodegeneration is the progressive loss of structure or function of neurons, including death of neurons. Many neurodegenerative diseases – including amyotrophic lateral sclerosis, Parkinson's disease, Alzheimer's disease, and Huntington's disease – occur as a result of neurodegenerative processes.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Neurodegeneration</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:12387894</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:20202123</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hp:HP:0002180</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00028">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">soluble oligomeric forms of the amyloid beta peptide known as amyloid-derived diffusible ligands (ADDLs) are the toxic species responsible for neurodegeneration associated with Alzheimer's disease.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">amyloid-beta derived diffusible ligands</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ADDL</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:19188609</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00029">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">increased secretion of the pancreatic hormone amylin</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hyperamylinemia</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23794448</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00030">
<rdfs:subClassOf rdf:resource="#CONSOC16"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">APOE e4 is a variant of APOE, it's APOE-ε4 (arg112, arg158).</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">APOE e4</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:22701550</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00031">
<rdfs:subClassOf rdf:resource="#CONSOC6"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">N-AcGIP is a rat hormone that is an agonist of GIP</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">N-AcGIP</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18234983</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00032">
<rdfs:subClassOf rdf:resource="#CONSOC6"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pro3-GIP is a rat hormone that is an agonist of GIP</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pro3-GIP</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AKOS034831571</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">[Pro3]-GIP (Rat)</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18234983</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">inchi:InChI=1S/C226H343N61O64S/c1-21-115(12)181(285-216(341)165(109-289)279-201(326)151(92-126-63-67-131(293)68-64-126)266-210(335)163(102-179(309)310)276-215(340)164(108-288)280-221(346)183(117(14)23-3)284-214(339)153(91-124-48-28-25-29-49-124)277-222(347)184(121(18)290)281-175(302)107-247-217(342)166-60-45-84-287(166)224(349)120(17)251-188(313)134(232)89-125-61-65-130(292)66-62-125)219(344)250-119(16)187(312)254-146(77-85-352-20)197(322)274-160(99-176(303)304)208(333)258-141(58-38-43-82-231)198(323)283-182(116(13)22-2)220(345)261-142(59-44-83-243-226(240)241)191(316)259-144(70-74-168(234)295)195(320)260-145(71-75-169(235)296)196(321)273-161(100-177(305)306)209(334)267-152(90-123-46-26-24-27-47-123)213(338)282-180(114(10)11)218(343)278-159(98-173(239)300)207(332)268-155(94-128-104-245-136-53-33-31-51-133(128)136)203(328)264-149(87-112(6)7)200(325)263-148(86-111(4)5)199(324)249-118(15)186(311)253-143(69-73-167(233)294)194(319)255-137(54-34-39-78-227)189(314)246-106-174(301)252-138(55-35-40-79-228)190(315)256-139(56-36-41-80-229)193(318)271-157(96-171(237)298)206(331)275-162(101-178(307)308)211(336)269-154(93-127-103-244-135-52-32-30-50-132(127)135)202(327)257-140(57-37-42-81-230)192(317)270-156(95-129-105-242-110-248-129)204(329)272-158(97-172(238)299)205(330)265-150(88-113(8)9)212(337)286-185(122(19)291)223(348)262-147(225(350)351)72-76-170(236)297/h24-33,46-53,61-68,103-105,110-122,134,137-166,180-185,244-245,288-293H,21-23,34-45,54-60,69-102,106-109,227-232H2,1-20H3,(H2,233,294)(H2,234,295)(H2,235,296)(H2,236,297)(H2,237,298)(H2,238,299)(H2,239,300)(H,242,248)(H,246,314)(H,247,342)(H,249,324)(H,250,344)(H,251,313)(H,252,301)(H,253,311)(H,254,312)(H,255,319)(H,256,315)(H,257,327)(H,258,333)(H,259,316)(H,260,320)(H,261,345)(H,262,348)(H,263,325)(H,264,328)(H,265,330)(H,266,335)(H,267,334)(H,268,332)(H,269,336)(H,270,317)(H,271,318)(H,272,329)(H,273,321)(H,274,322)(H,275,331)(H,276,340)(H,277,347)(H,278,343)(H,279,326)(H,280,346)(H,281,302)(H,282,338)(H,283,323)(H,284,339)(H,285,341)(H,286,337)(H,303,304)(H,305,306)(H,307,308)(H,309,310)(H,350,351)(H4,240,241,243)</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubchem.compound:131954578</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">smiles:CCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(C(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CCCCN)C(=O)NC(CC6=CNC=N6)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(C)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(CC7=CC=C(C=C7)O)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)CC)NC(=O)C(CC8=CC=CC=C8)NC(=O)C(C(C)O)NC(=O)CNC(=O)C9CCCN9C(=O)C(C)NC(=O)C(CC1=CC=C(C=C1)O)N</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00033">
<rdfs:subClassOf rdf:resource="#CONSOC21"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PI3K-Akt signaling pathway is an intracellular signaling pathway important in regulating the cell cycle.It is described in KEGG.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PI3K-Akt signaling pathway</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:22013558</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">kegg.pathway:hsa04151</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00035">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Argyrophilic grain disease (AGD) is an under-recognized, distinct, highly frequent sporadic tauopathy, with a prevalence reaching 31.3% in centenarians.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Argyrophilic Grain Disease</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AGD</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:15658002</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00036">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Granulovacuolar degeneration (GVD) is one of the pathological hallmarks of Alzheimer's disease (AD), and it is defined as electron-dense granules within double membrane-bound cytoplasmic vacuoles.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">granulovacuolar degeneration</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">GVD</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17455299</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hp:HP:0002528</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00037">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mitochondria function disorder</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mitochondrial dysfunction</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:19885299</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00038">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Insoluble fibrous protein aggregates exhibiting beta sheet structure.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">amyloid-beta fibrils</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:19158505</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0003-4423-4370</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00039">
<rdfs:subClassOf rdf:resource="#CONSOC27"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">a peptide derived from mouse laminin alpha 1 protein (seq:RKRLQVQLSIRT, chain:2719–2730)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AG73</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:20615691</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
<bel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">p(MGI:Lama1, frag(2719_2730))</bel>
</owl:Class>
<owl:Class rdf:about="#CONSO00040">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Notch intracellular domain is the intracellular region of notch receptor.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Notch intracellular domain</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:20883690</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00041">
<rdfs:subClassOf rdf:resource="#CONSOC19"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">YENTY is the endocytosis motif of Amyloid precursor protein.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">YENPTY endocytosis motif (APP)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">YENPTY</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18650430</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00042">
<rdfs:subClassOf rdf:resource="#CONSOC24"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Soluble amyloid precursor protein</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">sAPP-beta</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">soluble amyloid precursor protein</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:21606494</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00043">
<rdfs:subClassOf rdf:resource="#CONSOC0"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A growth factor is a naturally occurring substance capable of stimulating cellular growth, proliferation, healing, and cellular differentiation. Usually it is a protein or a steroid hormone. Growth factors are important for regulating a variety of cellular processes.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">growth factor</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:14678766</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncit:C20424</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">umls:C0018284</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00044">
<rdfs:subClassOf rdf:resource="#CONSOC28"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoforms containing 3 tubulin binding repeats</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3R tau</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23407988</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00045">
<rdfs:subClassOf rdf:resource="#CONSOC28"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoforms containing 4 tubulin binding repeats</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4R tau</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23407988</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00046">
<rdfs:subClassOf rdf:resource="#CONSOC19"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A hexapeptide motif located in the R2, that promotes the formation of PHF</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VQIINK motif</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PHF6* </skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00047">
<rdfs:subClassOf rdf:resource="#CONSOC19"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A hexapeptide motif located in the R3, that promotes the formation of PHF</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">VQIVYK motif</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PHF6</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00048">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Extracellular NFT remains after neuron death, considered to be the last stage of NFT-related pathological activity.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ghost tangles</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:8431763</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23407988</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00049">
<rdfs:subClassOf rdf:resource="#CONSOC5"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Pretangles are cytoplasmic tau immunoreactivity in neurons without apparent formation of fibrillary structures. In Alzheimer disease, such tau deposition is considered to represent a premature state prior to fibril formation (AD-pretangles), later to form neurofibrillary tangles and finally ghost tangles.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pretangles</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:23407988</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:24612177</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00050">
<rdfs:subClassOf rdf:resource="#CONSOC12"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Corresponding roughly to the N-terminal part of the tau molecule, consisting mainly of acidic residues and containing two distinct alternatively spliced N-terminal inserts.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">projection domain</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">MAP2/Tau projection</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:28386764</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">interpro:IPR013588</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00051">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A constitutively active splicing isoform of RAC1 (Ras-related C3 botulinum toxin substrate 1), first identified in breast and colon cancer.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">RAC1b</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:22142809</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P63000-2</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00052">
<rdfs:subClassOf rdf:resource="#CONSOC25"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A heterotetrameric adapter protein complex involved in cargo-internalization during clathrin-mediated endocytosis. Composed of alpha and beta subunits (large adaptins), mu and sigma subunits (minor adaptins).</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">AP-2 complex</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:27260836</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">go:GO:0030122</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00053">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Longest tau isoform in human brain, most commonly used as the conventional tau.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoform F (441 aa)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2N4R</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">htau40</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-associated protein tau isoform 2</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncbiprotein:NP_005901</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P10636-8</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00054">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Human fetal tau isoform.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoform Fetal-tau (352 aa)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0N3R</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">htau23</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-associated protein tau isoform 4</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncbiprotein:NP_058525</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P10636-2</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00055">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Human brain tau isoform, derived from alternative splicing.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoform B (381 aa)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1N3R</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">htau37</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-associated protein tau isoform 7</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncbiprotein:NP_001190180</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P10636-4</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00056">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Human brain tau isoform, derived from alternative splicing.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoform D (383 aa)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0N4R</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">htau24</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-associated protein tau isoform 3</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncbiprotein:NP_058518</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P10636-6</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00057">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Human brain tau isoform, derived from alternative splicing.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoform C (410 aa)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">2N3R</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">htau39</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-associated protein tau isoform 8</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncbiprotein:NP_001190181</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P10636-5</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00058">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Human brain tau isoform, derived from alternative splicing.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Tau isoform E (412 aa)</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">1N4R</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">htau34</skos:altLabel>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">microtubule-associated protein tau isoform 5</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:17493042</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">ncbiprotein:NP_001116539</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P10636-7</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0001-9661-5277</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00059">
<rdfs:subClassOf rdf:resource="#CONSOC24"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">?</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Serpin-enzyme complex receptor</rdfs:label>
<skos:altLabel rdf:datatype="http://www.w3.org/2001/XMLSchema#string">SEC-R</skos:altLabel>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:2160076</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:15160835</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-0303-8616</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00060">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">inflammatory response in the brain and nervous tissue.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">neuroinflammation</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:26306439</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">go:GO:0150076</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00061">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">happens when a biological, physical or chemical agent cause any adverse effect on the structure and function of the nerves system.</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">neurotoxicity</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:18440072</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00062">
<rdfs:subClassOf rdf:resource="#CONSOC20"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">when the neurite is unable it outgrow and extend</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">neurite retraction</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:19022228</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-3034-9970</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00063">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">the APP gene is located on chromosome 21 in humans with three major isoforms arising from alternative splicing [3]. These are APP695, APP751 and APP770 (containing 695, 751, and 770 amino acids, respectively)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">APP695</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:21214928</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P05067-4</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-6117-4413</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00064">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">the APP gene is located on chromosome 21 in humans with three major isoforms arising from alternative splicing [3]. These are APP695, APP751 and APP770 (containing 695, 751, and 770 amino acids, respectively)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">APP751</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:21214928</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P05067-8</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-6117-4413</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00065">
<rdfs:subClassOf rdf:resource="#CONSOC17"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">the APP gene is located on chromosome 21 in humans with three major isoforms arising from alternative splicing [3]. These are APP695, APP751 and APP770 (containing 695, 751, and 770 amino acids, respectively)</rdfs:comment>
<rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">APP770</rdfs:label>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pubmed:21214928</skos:related>
<skos:related rdf:datatype="http://www.w3.org/2001/XMLSchema#string">uniprot.isoform:P05067-1</skos:related>
<author rdf:datatype="http://www.w3.org/2001/XMLSchema#string">orcid:0000-0002-6117-4413</author>
</owl:Class>
<owl:Class rdf:about="#CONSO00066">
<rdfs:subClassOf rdf:resource="#CONSOC25"/>
<rdfs:comment rdf:datatype="http://www.w3.org/2001/XMLSchema#string">gamma-secretase is a high molecular weight complex minimally composed of four components: presenilins (PS), nicastrin, anterior pharynx defective 1 (APH-1), and presenilin enhancer 2 (PEN-2)</rdfs:comment>