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DESCRIPTION
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Package: pram
Title: Pooling RNA-seq datasets for assembling transcript models
Version: 1.1.3
Authors@R: c(
person( given="Peng", family="Liu", email = "[email protected]",
role = c("aut", "cre")),
person( given="Colin N.", family="Dewey", role = c("aut")),
person( given="Sündüz", family="Keleş", role = c("aut")) )
Description: Publicly available RNA-seq data is routinely used for
retrospective analysis to elucidate new biology. Novel transcript
discovery enabled by large collections of RNA-seq datasets has emerged as
one of such analysis. To increase the power of transcript discovery from
large collections of RNA-seq datasets, we developed a new R package named
Pooling RNA-seq and Assembling Models (PRAM), which builds transcript
models in intergenic regions from pooled RNA-seq datasets. This package
includes functions for defining intergenic regions, extracting and pooling
related RNA-seq alignments, predicting, selected, and evaluating
transcript models.
License: GPL (>= 3)
Encoding: UTF-8
LazyData: true
URL: https://github.com/pliu55/pram
BugReports: https://github.com/pliu55/pram/issues
Depends: R (>= 3.6)
Imports: methods,
BiocParallel,
tools,
utils,
data.table (>= 1.11.8),
GenomicAlignments (>= 1.16.0),
rtracklayer (>= 1.40.6),
BiocGenerics (>= 0.26.0),
GenomeInfoDb (>= 1.16.0),
GenomicRanges (>= 1.32.0),
IRanges (>= 2.14.12),
Rsamtools (>= 1.32.3),
S4Vectors (>= 0.18.3)
RoxygenNote: 6.1.0
Suggests: testthat,
BiocStyle,
knitr,
rmarkdown
Collate: 'Param.R'
'Transcript.R'
'buildModel.R'
'defIgRanges.R'
'evalModel.R'
'prepIgBam.R'
'runPRAM.R'
'selModel.R'
'util.R'
VignetteBuilder: knitr
biocViews: Software, Technology, Sequencing, RNASeq
SystemsRequirements: buildModel() and runPRAM() functions require external
software Cufflinks, StringTie, and/or TACO. For details, please see the
'Required external software' section in vignette's
'Building transcript models: buildModel()'.